PubMed Health⌕ Search

Biomedical subjects

R Spaić

Publications and source records attributed to R Spaić.

At least 19 recordsLinked to original sources
PubMed1993

Evaluation of left ventricular diastolic function by radionuclide ventriculography in patients with coronary artery disease.

Radionuclide ventriculography (RNV) was used to assess the peak filling rate (PFR) in 20 patients with coronary artery disease (CAD). Dipyridamole RNV was used in 5 normal subjects and 10 patients with CAD with the view to evaluating PFR increase. Significant difference in PFR values was established between normal subjects and CAD patients. Decreased value of PFR was found in 78% CAD patients, and 72% of them had normal ejection fraction (EF). During dipyridamole RNV increase of PFR was not significantly different between normals and CAD patients. The peak filling rate is a very sensitive indicator of LV dysfunction in CAD patients, and is useful in early detection of abnormalities in diastolic function in CAD patients.

Adult↗
PubMed1991

Evaluation of diagnostic reliability of radionuclide phlebography using 99mTc-MAA to detect deep venous thrombosis; its role in establishing indications for inferior vena cava filter implantation.

Radionuclide phlebography (RNP) of the lower extremities and pelvis was performed using 99mTc-MAA in 40 patients with pulmonary thromboembolism. Deep venous thrombosis (DVT) was found in all patients, more frequently in the right calf and in the left iliac veins in 20 patients (55%). RNP and contrast phlebography (CP) were performed in 18 patients and confirmed the presence of DVT in all cases. The greatest specificity of RNP was obtained in the left (92.4%) and in the right pelvis (80%). In 12 of 18 patients in whom a cava filter was implanted, specificity of RNP was 100% for the left thigh and 91.7% for other localizations. In establishing indications for cava filter implantation, RNP should be performed prior to CP and bilaterally, but in case of non-indicated CP, RNP findings should be sufficient.

Female↗
PubMed1976

[Stomatologic preparation of patients with malignancies of the maxillofacial region for radiation therapy].

A series of 3456 patients with malignant tumours of the maxillofacial region have been treated at the Clinic for Maxillofacial and Oral Surgery of the Military Medical Academy, Stomatological Clinic of the M.M.A. and Radiological Institute of Medical Faculty in Belgrade. The most frequent localization was lips and mucosa of the oral cavity, 77,9%. The irradiation therapy was applied in 42,3% of the patients and combined surgery and irradiation therapy in 28,6% Postirradiation changes of the oral cavity mucosa were found in 25% of the patients, teeth changes in 50% and Candida albicans was found in 56% of the patients. In order to prevent irradiation and postirradiation complications, all the patients with malignant tumours foressen for irradiation therapy should undergo a detailed stomatological examination and sanation of the oral cavity and teeth. The authors advocate team work in establishing the diagnosis and treating in which an important place should have stomatologist.

Humans↗
PubMedDate not supplied

[Experimental study of the pathogenesis of frostbite. Part II. Role of the sympathetic-adrenergic system in tissue reperfusion immediately after thawing].

The authors have investigated the role of sympathetic-adrenergic system in reperfusion of muscular tissue of the feet of Wistar rats immediately after thawing using alpha adrenergic blocker phentolamine methanesulfonate (Regitin). Cryoinjury was applied over an experimental model of local, controlled freezing of different intensity for certain experimental groups. Blood flow through microcirculation was measured by scintigraphy, following Tc-99m-pertechnetate clearance that was given in muscular mass of frozen right, as well as unfrozen left feet of rats. Results obtained in some experimental groups were compared mutually, as well as with the control group that was not exposed to cryoinjury. The investigations have revealed that immediately after thawing existed significant reduction, non-dependent of the intensity of freezing, in blood flow in microcirculation of both frozen and unfrozen feet of rats compared to the control group. Significant increase of microcirculatory blood flow in unfrozen feet was caused by blockade of sympathetic-adrenergic system, while the blood flow remained unchanged in the frozen ones. The reduction of blood flow in microcirculation of frozen tissues immediately after thawing was not associated with sympathetic-adrenergic factor.

Adrenergic alpha-Antagonists↗
PubMedDate not supplied

[Evaluation of perfusion of transplanted microvascular flaps using radionuclide arteriography].

Microvascular flap by its autonomous circulation, following the transplantation in recipient region, provides the quantity of blood sufficient for nutritive needs of flap, but it also provides additional blood supply in the surrounding of recipient region. The evaluation of the relation of the tissues perfusion of transferred microvascular flaps and the tissues of surrounding recipient region was done in 33 patients, 15.24 months after the transplantation of microvascular flaps, by radionuclide angiography using Tc-99m in the form of MAA HAS or pertechnetate at the Clinic for Plastic Surgery and Burns of Military Medical Academy (MMA) and at the Institute for Nuclear Medicine of MMA. Cutaneous, myocutaneous and osteocutaneous microvascular flaps were transferred to the foot, lower leg and in the head region. The obtained results revealed that the perfusion of the tissue of transferred flaps was better than the perfusion of the recipient region surrounding (232%). Perfusion of myocutaneous flaps related to the type of microvascular flap was the highest and came to 244% of the perfusion of the recipient region surrounding. Accumulation of radiopharmaceuticals in the tissue of the flap was homogenous in 19 (57.57%) flaps.

Adult↗
PubMedDate not supplied

[Use of 99mTc-pyrophosphate and coronarography in the diagnosis of simultaneous myocardial infarct of the right and left cardiac ventricles].

Myocardial scintigraphy was performed using 99m-Tc-pyrophosphate in 50 patients with suspected coexisting right ventricular and left inferior ventricular heart infarction and in 50 patients with left inferior ventricular infraction only. In all survived patients additional selective coronarography was performed and in all died patients autopsy was performed. The aim of the study was to evaluate reliability of myocardial scintigraphy using 99m-Tc-pyrophosphate in the diagnosis of coexisting infarction of both heart ventricles. In a group of patients with coexisting right and left ventricular infarction (45 proved by coronarography, and 5 by autopsy), scintigraphic finding was confirmed in 46 (93%) patients. In all 50 patients with left inferior ventricular infarction, scintigraphic finding was confirmed in 48 of them by coronarography and in 2 by autopsy (100%). Of 4 patients with false negative scintigraphic finding 2 were treated with fibrinolytic therapy immediately after admission and in 2 diffuse occlusive changes were found on all three blood vessels by coronarography. It has been concluded that myocardial scintigraphy using 99m-Tc-pyrophosphate is a very sensitive (92%), specific (100%), exact (96%), simple and safe diagnostical method in detecting coexisting acute infarction of both heart ventricles.

Coronary Angiography↗
PubMedDate not supplied

[Rational treatment of oral and dental diseases in war].

The treatment of oral and dental diseases during the war is complicated with many aggravating circumstances, such as: a great number of ill and injured persons per dental team; limited handling of all kinds of material, lack of time, etc. The paper deals with the epidemiological research of the most frequent oral diseases in soldiers of the Yugoslav Army. The need for dental care was established upon these data. Since the discrepancy between the requests and possibilities is obvious, it is emphasized that the rationalization of treatment of oral and dental diseases can give favourable results even in war conditions.

Adult↗