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Biomedical subjects

R T Schweizer

Publications and source records attributed to R T Schweizer.

At least 91 records · Page 5Linked to original sources

Management of antacid impactions in hemodialysis and renal transplant patients.

Ten cases of intestinal obstruction caused by antacid impactions in renal transplant and hemodialysis patients were added to 16 reports in the literature. In six instances, operative intervention was necessary because of failure of vigorous medical therapy. Three patients who died had perforation of the colon at sites of stercoral ulceration due to firm antacid impactions. Aggressive medical and surgical management of constipation and fecal impaction is recommended. The outlook is grim once colonic perforation has occurred.

Adolescent↗

Use of antibiotics for prevention of Bacteroides fragilis wound sepsis in rats.

A Bacteroides fragilis wound sepsis model was developed in rats. Topical and parenteral administration of clindamycin, chloramphenicol, and carbenicillin were used prophylactically to eradicate bacteria from contaminated wounds. Topical clindamycin prevented bacterial growth in 15 of 34 wounds, while topical chloramphenicol and carbenicillin were not effective. Clindamycin injected into the wound margins or at a distal site prevented bacterial growth in 16 of 18 wounds and in a lower dose prevented growth of 50 per cent of 12 wounds. These results support the clinical use of clindamycin for the prevention of Bacteroides wound infection.

Administration, Topical↗

Pregnancy in renal transplant patients: a review.

A questionnaire survey and review of the literature show that pregnancy can be well tolerated in most women with renal transplants. Fifty-two per cent of the renal transplant recipients who became pregnant had full-term infants with no serious complications. With therapeutic abortions, excluded, 71% of the 308 pregnancies permitted to continue resulted in full-term infants. Rejection episodes were occasionally a serious problem, occurring in 9% of the pregnancies. Mechanical interference with renal excretion or preventing vaginal delivery occurred in 5.6% of the cases. Hypertension and proteinuria, often existing prior to pregnancy, became frequently increased during pregnancy. Infections not associated with rejection were common but easily controlled in most cases. Prematurity was frequent but related to renal function and the time interval from transplant to conception. The most serious infant complications were related to prematurity. Unknown is the future of these infants and their progeny because of their intrauterine exposure to immunosuppressive drugs.

Bacterial Infections↗

Fibrosis of a renal transplant ureter.

Ureteral obstruction following renal transplantation, although not a common occurrence, is a serious complication because of the single functioning kidney. Obstruction may be caused by ureterovesical stenosis, retroperitoneal fibrosis or adhesions, clot formation, pelvic lymphoceles or kinking of the ureter. A case is presented in which there was progressive partial ureteral obstruction caused by fibrosis and stricture of the transplant ureter, which were probably owing to rejection episodes.

Graft Rejection↗

Pyelolithotomy of a renal transplant.

A large calculus developed in a renal transplant patient and was removed by pyelolithotomy. Hyperparathyroidism was not present. Important factors to consider before performing a nephrolithotomy in a transplanted kidney are whether the transplant was a right or left kidney and the timing of the operation in relation to renal function and infection. The etiology for renal stone formation in renal transplant recipients includes hyercalciuria, renal tubular acidosis, antacid administration and infection.

Antacids↗

Mask wiggling as a potential cause of wound contamination.

Some operating-theatre staff have a habit of wiggling their surgical masks by moving their facial muscles. The field contamination which can result from this practice was studied. A firmly fitting, moulded, synthetic-fibre mask produced significant bacterial contamination of culture plates held beneath the mask, compared with that found on simultaneously exposed control plates placed nearby. Softer fibreglass masks produced less contamination when moved by facial muscles, and are more suitable for mask wigglers.

Face↗

Treatment of pelvic lymphoceles after renal transplantation by intraperitoneal marsupialization.

Pelvic lymphoceles following renal transplantation occurred in five of 70 recipients and were treated by intraperitoneal marsupialization. There were no complications other than one recurrence, which was successfully managed by a second marsupialization procedure. Intraperitoneal marsupialization avoids the prolonged wound drainage of external drainage methods, and appears to be the treatment of choice for large pelvic lymphoceles.

Humans↗

Decreased function of a renal transplant after influenza virus infection.

A sixteen year old female recipient of a renal transplant had decreased renal function one month after an influenza virus infection. An acute rejection episode induced by the viral infection was the probable cause. Renal function in transplant recipients should be carefully monitored for at least one month after viral infection.

Adolescent↗