Biomedical subjects

R Trinkmann

Publications and source records attributed to R Trinkmann.

At least 19 recordsLinked to original sources

PubMed1998

[Postoperative behavior of intraocular pressure after posterior Nd:YAG laser capsulotomy--critical evaluation in preventive administration of local carbonic anhydrase II inhibitor dorzolamide hydrochloride (Trusopt)].

BACKGROUND: The aim of the present study was to examine the influence of the topical carbonic anhydrase-II-inhibitor dorzolamide hydrochloride (Trusopt) in regarding to behaviour of intraocular eyepressure after Nd:YAG-laser-capsulotomy. PATIENTS AND METHODS: The study was carried out as a double-blind-test. In a period of nine months, 120 patients underwent Nd:YAG-laser-capsulotomy. One group was given dorzolamide hydrochloride (Trusopt), the other group (placebo) remained without medication. The intraocular pressure was measured before capsulotomy and four hours post-op. For statistical evaluation the t-test of not-associated spot-checks was performed. RESULTS: The prophylactic use of the topical carbonic anhydrase-II-inhibitor dorzolamide hydrochloride (Trusopt) after nd:YAG-laser-capsulotomy shows a highly significant lowering of intraocular pressure, i.e. 1.09 mm Hg in the average. CONCLUSIONS: It was demonstrated that a single dose of dorzolamide hydrochloride (Trusopt) after Nd:YAG-laser-capsulotomy could lower intraocular pressure significantly. Prophylactical usage of dorzolamide hydrochloride (Trusopt) is a useful method to prevent the increase of intraocular pressure and thus to protect the eye against hazardous damage.

Aged↗

PubMed1990

Refractive errors after cryotherapy in retinopathy of prematurity.

Because of acute retinopathy of prematurity 14 premature infants (900-1,630 g birth weight) were treated with cryocoagulation (10 children, both eyes; 4 only one eye) between 1976 and 1984 and were followed up until they were 2-7 years of age. The average refractive power of 20 eyes (those in which refraction could be determined) was -1.5 +/- 4.1 dptr. Twelve eyes (60.0%) were hyperopic (average: +1.3 +/- 0.4 dptr), and 8 eyes (40.0%) were myopic (average: -5.7 +/- 3.6 dptr). Three eyes in which cryocoagulation was done twice or three times because of a severe course developed pronounced myopia (greater than 7.0 dptr). When comparing both eyes of 4 children in whom cryotherapy had been carried out in only one eye, cryotherapy was found to have no influence on refractive errors (average anisometropia +0.4 +/- 0.4 dptr).

Birth Weight↗

PubMed1989

Peeling technique for cataracta secundaria associated with posterior chamber lenses.

A new method for removing a secondary cataract with a posterior chamber lens in situ was developed using a specially designed irrigation/aspiration handpiece. In two cases, a focal rupture of the posterior capsule without vitreous prolapse occurred. There were no other serious complications observed in 367 patients who were treated.

Cataract↗

PubMed1989

[Retinopathy of prematurity: long-term results following trans-conjunctival cryocoagulation].

Between January 1977 and December 1984, 2173 premature infants with a birthweight of under 2500 g were examined. In accordance with the Patz and Payne classification, retinopathy of prematurity (ROP) was diagnosed in 6.2% of the cases. In 1.5% ROP was at stage III; 26 children (47 eyes) in stage III who were showing further deterioration were treated by means of transconjunctival cryocoagulation, mostly with local anesthesia. We were able to examine 18 patients (32 treated eyes) during a follow-up period from 1985 to 1986. In 56%, it was possible to prevent the development of cicatricial stages altogether by cryopexy treatment; 31% developed cicatricial stage I and II with little impairment of vision. Four of 32 eyes (13%) showed extensive amotio retinae with retrolental membranes (cicatricial stage IV-V). As apposed to light and laser coagulation, cryopexy is less time consuming because there are fewer focal points. If local anesthesia is used, there is a further advantage, as general anesthesia involves other numerous risks, particularly for premature infants.

Child↗

PubMed1989

[Automatic biometry and keratometry in comparison with the manual technic].

In order to determine the power of intraocular lenses more easily prior to cataract surgery, we compared the results obtained by automatic measurement of the corneal refractive power by the Humphrey Autokeratometer with manually obtained measurements using the Zeiss ophthalmometer. Similarly, the axial length was determined by automatic measurements using the Digital B System IV (Cooper Vision) and manual measurements using the Ophthascan S (Biophysic Medical). Statistical evaluation showed that there were no significant differences in the corneal refractive power determined by the two methods or in the IOL power calculated using the SRK formula. Therefore, automatic measurement of both corneal refractive power and axial length following the above method can be a useful alternative to the preoperative determination of the IOL power.

Humans↗

PubMed1989

[Follow-up after enucleation in choroid melanoma].

We report on 31 patients who underwent enucleation between 1976 and 1984 for uveal melanoma and had a mean follow-up of 107 months. There was no irradiation to the globe or orbit prior to enucleation, which was done under general anesthesia. Histology showed that: the average diameter of the tumors was 10.6 mm and the average height 6.2 mm. There were 3 cases of spindle-cell A-type tumors, 19 of spindle-cell B, 2 of mixed cell types, and 7 cases of mixed cell types with epithelioid cell dominance or epithelioid cell tumors. In September 1988, 9 patients (29%) had died as of a result of metastases from the melanoma; 4 patients who died were found to have another malignant tumor; 1 patient died due to cerebral apoplexia; 1 patient died 8 days after enucleation due to unknown causes. The survival curve was based on the Kaplan-Meier method.

Adult↗

PubMed1988