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Biomedical subjects

R Wald

Publications and source records attributed to R Wald.

15 recordsLinked to original sources

Visual attention in infant monkeys: effects of dietary fatty acids and age.

Effects of dietary essential fatty acids on visual attention were explored longitudinally in infant rhesus monkeys with a visual paired-comparison paradigm. Sets of primate faces and of patterns were presented at Weeks 2, 5, 9, and 13 to 9 infants deficient in omega-3 fatty acids and 8 fed a standard nursery diet. Familiarization to 1 member of each pair preceded simultaneous presentation of both stimuli. Infants fed the deficient diet showed longer individual looks in both immediate and 24-hr tests. Duration of looks decreased with age to familiar but not to novel stimuli. The proportion of time looking at the novel stimulus (% novel) increased with age but was not affected by diet. Look duration and % novel were differentially affected and may reflect different underlying processes.

Aging

A treatment model for women substance users.

This paper sets forth a multifaceted program which consists of drug user women-centered counseling plus ancillary services based on the five basic steps of Freire's empowerment theory. The program is designed to increase self-awareness, skills, and knowledge acquisition, to reduce feelings of isolation by broadening interpersonal networks, includes activities to enhance assertiveness and communication skills, and parenting education to counteract inappropriate mother-child interaction as well as to positively influence role modeling. Both transportation and child care are recommended ancillary services.

Adult

Circuit for measurement of instantaneous frequency.

This paper describes a circuit that measures the instantaneous frequency of a pulse train applied to the input. Analog outputs are provided that are linearly proportional to the interval between successive pulses and to the reciprocal of that same interval. The design is based upon well-established operational amplifier circuits and can be built with readily available components. The range over which the circuit operated can be changed by the selection of a single resistor, and the initial calibration requires the adjustment of only three components.

Electronics, Medical

Dual-path capacitance compensation network for microelectrode recordings.

Commercially available microelectrode preamplifiers have a built-in capacity compensation circuit. When a shielded cable is utilized to transmit the signal from the microelectrode to the preamplifier the compensative ability of this circuit may be inadequate and may result in a less than desired frequency response. We describe a dual-path capacitance compensation circuit that resolves this problem without impairment of the shielding properties.

Electronics, Medical

Nesidioblastosis associated with insulin-mediated hypoglycemia in an adult.

Nesidioblastosis, the process of differentiation of pancreatic islets from ductular epithelium, is a well-described cause of insulin-mediated hypoglycemia in neonates and infants, but not in adults. A 58-yr-old woman with characteristic clinical features of fasting hypoglycemia had inappropriately elevated plasma immunoreactive insulin levels during symptomatic episodes of fasting hypoglycemia. Angiography, palpation at laparotomy, and resection of the distal three-quarters of the pancreas provided no evidence of a tumor. Pathologic examination of the resected pancreas revealed the findings of nesidioblastosis, i.e., budding of islets from the wall of ductules, and also increased number and size of islets and abnormal shape and location of islets. An entire spectrum of islet cell abnormalities including nesidioblastosis can cause insulin-mediated hypoglycemia in adults, as it does in neonates and infants.

Adenoma, Islet Cell