A scientific supercourse.
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Biomedical subjects
Publications and source records attributed to Ronald E Laporte.
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OBJECTIVE: The aim of this study was to search for the seasonal and geographic variations in epidemics of type 1 diabetes in China. RESEARCH DESIGN AND METHODS: Incidence data from 22 type 1 diabetes registration centers across China were analyzed. A Poisson regression model with a sine wave function was applied to evaluate the seasonal trends. A scan statistic was used to examine the occurrence of an epidemic. RESULTS: There was a significant cyclic trend of incidence of type 1 diabetes in China. The northern area had a higher incidence rate than the southern area. Epidemics were discovered in Dalian and Shenyang from late 1992 to late 1993. CONCLUSIONS: There was a strong association of climate and incidence of type 1 diabetes in China, whereby the incidence was higher in the colder areas and in the winter months. Evidence of epidemics existed in two centers in 1992--1993. It is critical to identify the epidemics early and determine the causes of epidemics.
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