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Biomedical subjects

S A Andreeshchev

Publications and source records attributed to S A Andreeshchev.

At least 19 recordsLinked to original sources
PubMed2005

[Portal reconstruction in hepatectomy with resection of portal vein].

Modern issues of the portal vein resection while hepatectomy conduction are enlighten. The indications for resection of region of the portal vein branches confluence were substantiated, various methods of portoplasty were depicted. New methods of the portal tract passability restoration in discrepancy of diameters of the sutured portal vein portions were proposed. The results of hepatectomy with the portal vein resection were studied up.

Angiography↗
PubMed2004

[Re-laparotomy and damage control during surgical treatment of postoperative intra-abdominal purulent-septic complications].

The issues of pathophysiology, diagnosis and surgical treatment of postoperative intraabdominal purulent-septic complications were suggested. Noncontrolled abortion of mediators with subsequent development of inflammation and damage in the organs, localized far from primary focus, constitutes the main factor of the postoperative intraabdominal purulent-septic complications occurrence. In such a situation the intraabdominal hypertension and abdominal compartment syndrome also promote the deepening of multiple dysfunctions of organs due to mechanical failure of functions in respiratory, hemodynamical, excretional systems of the organism, what promotes the development of vicious circles and the cascade reactions, leading to exitus lethalis. The modern strategy and tactics of complex treatment of such patients is enlighted.

Abdominal Abscess↗
PubMed2004

[The role of endothelin-1 in the pathogenesis of septic shock in the abdominal sepsis].

Role of endoteline-1 (ET-1) in pathogenesis of septic shock (SS) was studied in 22 patients in the age from 34 to 58 years. There was shown, that ET-1 content in plasma depends on functional level of the adaptation-compensation reaction of organism as an answer on occurrence of SS in patients with abdominal sepsis. This is demonstrated by more high concentration of the index studied in the patients survived and also presence of correlative connection between ET-1 level in plasma of blood, indexes of middle arterial pressure and general peripheral resistance of vessels. There were received preliminary data, witnessing, that circulating cytokines, in particular, interleukin-8, stimulate the heightened production of ET-1 by endothelial cells, what probably in early terms the SS course constitutes the compensatory reaction, directed on elimination of pathogenic microorganisms, securing of reparative processes and maintenance of homeostasis.

Abdominal Abscess↗
PubMed2004

[The experience of diagnostic and surgical treatment of Barrett's oesophagus].

There were analyzed five-year late results of prospective investigation on surgical treatment of 23 patients, suffering long-segment Barrett's esophagus (BE). Esophagoplasty and esophagocardioplasty was performed in 7 (30.4%) patients and total fundoplication in combination with endoscopic ablation of metaplastic epithelium--in 16 (69.6%). Excellent and good results marks in 19 (827%) of patients, including those with antireflux operation, and satisfactory--in 4 (17.3%), witnessing high efficacy of surgical treatment in the BE correction.

Adult↗
PubMed2003

[Performance of restoration surgeries in postburn stenosis of the esophagus and stomach].

The thirty-years experience of treatment of 987 patients with postburn stenosis of the gut upper parts was summarized. Of the total amount of restorational operations performed in 431 patients there were: esophagoplasty using colon--in 313 (72.62%), small intestine--in 26 (6.04%), stomach--in 66 (15.32%), segment of colon and ileum on the vascular pedicle--in 10 (2.31%), autotransplantation of jejunal segment--in 2 (0.47%), esophagocardioplasty--in 5 (1.15%), plasty with application of local tissues--in 9 (2.09%). Total mortality had constituted 6.96%, but during last 12 years it had subsided down to 1.91% due to perfection of the operations technique performed, new procedures introduction, the anesthesiological support improvement, wide usage of prophylactic measures for possibly occurring complications.

Anastomosis, Surgical↗
PubMed2003

[Stomach shunting in the surgical treatment of pathologic obesity].

Gastric shunting (GS) constitutes one of the most effective surgical methods of treatment of morbid obesity. In USA and European countries GS constitutes standard bariatric intervention, in Ukraine these operations were not performed before. The technique of the most popular GS operations was depicted, own results of their application were presented.

Adult↗
PubMed2001

[Diagnosis and surgical treatment of secondary gastroesophageal reflux disease].

Examination and treatment was performed in 69 patients with secondary gastroesophageal reflux disease (GERD), 61 (88.4%) of whom were primarily operated on for achalasia of cardia and GERD. The choice of the operation method was based on complex examination of the patients. Due to conduction of preoperative preparation it was possible to perform the most physiological antireflux fundoplication operations in the patients.

Adult↗
PubMed2000

[Persisting viral infection, serum antibodies and chromosome instability in myasthenia].

There were examined 94 patients, aged from 22 to 68 years, with myasthenia, in whom morphological changes of thymic gland were revealed. In 89% of observations there was established the infectioning by cytomegalovirus, in 10%--hepatitis B, in 9%--hepatitis C. In 5% of patients there were observed coexistence of cytomegaloviral infection and hepatitis. In all the patients the trustworthy increase of the chromosomal aberrations frequency in comparison with spontaneous level of mutation was revealed. High diagnostic validity of chain reaction with polymerase in the viruses persistence determination was noted. The results of investigation of serous immunoglobulins to the virus neutralizing antibodies ratio may be applied for the indications elaboration in the lymphosorption and immunocorrection application in patients with myasthenia more than 4 years in course.

Adult↗
PubMed2000

[Antibacterial therapy of patients with inflammatory necrotic pancreatitis].

The infectionized necrotic pancreatitis (NP) course, complicated by localized and diffusive peritonitis, abscess and retroperitoneal phlegmon in 86 patients, was analyzed. Severity of state of patients according to the APACHE II scale was estimated. Recommendations for application of empirical and purposeful antibacterial therapy was elaborated. Total mortality for infectionized NP with complicated course was 25.5%.

Abdomen↗
PubMed2000

[Surgical treatment of gastroesophageal reflux disease in the presence of coexistent hiatal hernia].

Experience of treatment of coexistent hiatal hernia (HH) and gastroesophageal reflux disease (GERD) in 491 patients using simultant hernioplastic and antireflux operation was summarized. Complete fundoplication was performed in 478 (97.4%) patients, noncomplete one--in 13 (2.6%), cruroraphy--in 321 (65.4%), including complex method of hernioplasty--in 80 (16.3%). Postoperative mortality was 0.8% (4 patients). The tactical and methodical principles applied have permitted to guarantee the physiologicity and safety of the coexistent HH and GERD surgical treatment.

Adolescent↗
PubMed2000

[Results of partial shunting in liver cirrhosis].

Complex hemodynamical investigations were conducted in 32 patients before the operation and after performance of partial portosystemic shunting (in 8--mesentericocaval anastomosis was done, in 10--central splenorenal one, in 12--splenorenal side-to-side, in 2--lowermesenterial-renal). The formation of anastomosis 8-10 mm in diameter had promoted the sufficient reduction of pressure in v. porta, preservation in it the hepatopetal blood flow, prophylaxis of uncontrolled occurrence of portosystemic encephalopathy, had secured the stable hepatic function during 36 months.

Humans↗
PubMed2000

[The role of the intestine in the pathogenesis of the multi-organ dysfunction syndrome in diffuse peritonitis].

Extraction of oxygen (O2), ultrastructural organization of intestinal macrophages and translocation of microorganisms were studied on 50 male rats of Wistar line in 2, 6, 12, 24 and 48 hours after the stimulation operation performance (control group) and modelling of an acute purulent peritonitis (APP)--basic group. Increase of common and lowering of intestinal extraction of O2 in early terms of the APP occurrence, accompanied by intensive reproduction of microorganisms and change of intestinal biocenosis, was noted. These infringements correlated with translocation of microorganisms through mesenteric lymphatic nodes--ductus toracicus--systemic blood flow (basic way) in term up to 24 hours and through portal vein--hepar--systemic blood flow (additional way)--up to 48 hours after the APP beginning.

Animals↗
PubMed1999

[Splanchnic circulation after distal splenorenal anastomosis in hepatic cirrhosis].

While the result estimation of the distal splenorenal anastomosis formation operation, done in 12 patients according to the W. D. Warren method and in another 12 patients--according to the method, modified by K. Inokuchi, it was established that the hepatic portal perfusion loss causes compensational enhancement of blood flow in a. hepatica, including while the standard method application--by 22% and the modified one--by 8%. Doing the splenorenal venous disconnection improves the patients' quality of life due to the incidence rate of portosystemic encephalopathy reduction by 8.3%, and in this circumstances the life span and the hemorrhage recurrency rate do not differ with such while using the standard method.

Humans↗