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Biomedical subjects

S A Andreeshchev

Publications and source records attributed to S A Andreeshchev.

At least 37 records · Page 2Linked to original sources

[Strategies and techniques in the correction of the enteral insufficiency in peritonitis and acute ileus].

The correction principles of enteral insufficiency, playing essential role in the infectional-toxical shock and polyorganic insufficiency occurrence were elaborated basing on the analyses of the surgical treatment of 257 patients with peritonitis and an acute ileus. Application of the proposed tactics of surgical aid for patients, including the original methods of the gut intubation, had permitted to lower the lethality from 30.2 to 18.5%, to improve the treatment results.

Acute Disease↗

[The role of the intestines in the pathogenesis of acute pancreatitis: oxygen extraction and bacteria translocation in rats].

In experiment on 40 male rats of the Wistar line there was investigated the oxygen extraction (O2) and the bacteria translocation in 30 min, 2, 6, 12 and 24 hours after the stimulating operation (control group) and simulation of the ductal-hypertensive form of an acute experimental pancreatitis (AEP)--the main group. The data obtained witness the general extraction of O2 raising by 222% (P < 0.001) at average and lowering of its intestinal extraction in 30 min and 2 hours (by 33 and 31% at average, P < 0.05) and its raising in 24 hours by 138% (P < 0.001) at average also. These disorders had correlated with velocity of the intestinal E. coli reproduction and with the bacteria translocation on the way intestine-->mesenterial lymph nodes in 6 hours after the disease occurrence with preservation of the lymph nodes and the liver barrier function in the AEP duration over 24 hours. The data obtained had permitted to substantiate the necessity of the remedial measures complex application, directed on the frequency of purulent complications lowering.

Animals↗

[Acute biliary pancreatitis. Diagnosis and course of treatment].

The results of surgical treatment of 320 patients with an acute biliary pancreatitis are analysed. The therapeutic-tactical algorythm, using miniinvasive endoscopical interventions, is elaborated. Mortality for pancreatitis in systemic-toxical phase have constituted 10.1%, and in septical one--33.3%.

Acute Disease↗

[State of stress-limiting and stress-responsive systems of the body in pancreatic necrosis during systemic-toxic phase].

Results of dynamic investigation of beta-endorphins and hormonal state were analysed in 34 patients with pancreonecrosis aged from 23 to 54 years. The dependency of this indexes on the severity of clinical course and presence of complications was determined. The correction ways of injurious action of stress-reaction in pancreonecrosis were proposed.

Adrenal Cortex Hormones↗

[Prognostication of the course of pancreatogenic shock in a dynamic study of central hemodynamics indices in patients with pancreatic necrosis during enzymatic toxemia stage].

The investigation of central haemodynamics indexes dynamics with the use of the developed automatized system in 65 patients with pancreonecrosis was conducted for the aim of disease course prognostication and differentiated prescription of cardiotonics. Three stages of circulatory disorders were established. The possibility of patient's death significantly increases in the presence of prolonged depression of cardiac output when rapid effect of conservative therapy is absent.

Adult↗

[Pylorus-reconstructing operations in complicated gastric and duodenal ulcer].

The results of treatment of 185 patients with complicated gastric and duodenal ulcer disease have been analysed. The results of operative treatment in 132 patients followed up for the period of from 1 to 7 years were studied. In gastric ulcer, resection of the stomach with preservation of the pyloric sphincter, or its reconstruction by means of the flaps taken from the antrum, is indicated; in duodenal ulcer--vagotomy, ulcer excision added by pylorus-preserving and pylorus-reconstructing methods of drainage operations.

Anastomosis, Surgical↗

[Prognosis of the development and prevention of primary post- operative peptic stricture of the esophagus].

Examined were 58 patients with primary postoperative peptic esophageal stricture (PPPES). The ulcer disease of pyloroduodenal location and impaired function of the esophagus were the leading causes of a stricture. The prognostic algorithm for the PPPES development, which considers the presence of hiatal hernia, severe disorders in gastric evacuation and vomiting, pronounced weakness of a patient, severe complications of the ulcer disease before the operation, has been developed. The prophylactic measures in given pathology are suggested.

Adolescent↗