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Biomedical subjects

S A Khrustalev

Publications and source records attributed to S A Khrustalev.

At least 37 records · Page 2Linked to original sources
PubMed1977

[Spontaneous neoplasms in guinea pigs].

The authors present an analysis of the data of foreign literature and the results of their personal studies of spontaneous neoplasms in 40 guinea pigs of national breeding observed during observed during a 5-year period. In 4 of them malignant tumors were diagnosed-lympholeucosis (2 cases), dermoid ovarian cysts and also cancer and adenoma of the adrenal cortex (in one animal). The neoplasms described developed in guinea pigs, aged over 4 years, and they are referred to as mostly common tumors in this species of animals.

Age Factors↗
PubMed1977

[Possible use of guinea pigs for the study of the blastomogenic activity of endogenous substances].

Mongrel guinea pigs were given 3-indolilacrilacid and 2-aminoacetophenon derivates of tryptophan which blastomogenic action was previously revealed in experiments on inbred mice. Both substances produced tumors in animals of the experimental groups earlier than in the control group, this fact showing both the preparations to have blastomogenic effect. The results of the investigation show the possibility of using guinea pigs for studying the blastomogenic action of weak cancerogenic agents to which the endogenic blastomogenic substances belong.

Acetophenones↗
PubMedDate not supplied

[Carcinogenic danger of zeolite from Kholinsk].

The carcinogenic activity of the enterosorbent optisorb (pure zeolite) and the biologically active food additive litovite [zeolite and rye brans (1:1)] based on zeolite-clinoptololite from the Kholinsk deposit was studied. The intrapleural three-fold administration of optisorb (20 mg x 3) to rats and the inclusion of optisorb (5% of the feed) and litovite (5 and 0.06%) into the feed showed that these agents had no carcinogenic activity.

Carcinogenicity Tests↗