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Biomedical subjects

S A Tikhodeev

Publications and source records attributed to S A Tikhodeev.

At least 37 records · Page 2Linked to original sources
PubMed1986

[Indicators of intraosseous pressure and venospondylography in the diagnosis of inflammatory diseases of the spine].

The measuring of the intraosseous pressure and venospondilography were included into the complex of examination of 82 patients in order to increase the efficiency of diagnostics and differentiation of osteomyelitis and tuberculosis of the vertebral column. The methods used considerably increased the reliability of diagnosis of these inflammatory diseases of the vertebral column.

Adolescent↗
PubMed1984

[Venospondylography in the diagnosis of epidural abscesses in spinal osteomyelitis].

Venospondilography following a modified method in combination with pneumomyelotomography was fulfilled in 1,5 patients with osteomyelitis of spine. Venospondilography was found to be more informative as compared with pneumomyelography and liquor dynamic tests. It can be used among other methods of preoperative diagnosis in patients with spine osteomyelitis complicated by spinal disorders.

Abscess↗
PubMedDate not supplied

[The role of somatosensory evoked potentials in evaluating the treatment of patients with degenerative-dystrophic diseases of the lumbosacral spine].

Somatosensory evoked potentials (SSEP) were dynamically studied through bilateral stimulation of n. tibialis at the cortical and spinal level in 160 patients with degenerative and dystrophic lumbosacral diseases. The study revealed significant changes in the peaks Pf, N21 and in the intervals Pf-N21 in 38 (23.75%) patients. The patients had generally vascular disorders as ascending arterial, venous or concomitant myeloradicopathies (the syndromes of venous or arterial ischemia of the epiconus or conus). There were SSEP no significant changes in the paralyzing ischiasis syndrome. Early decompressing operations on the vertebral column (within 1 to 3 months) led to reversal of neurological disorders in most patients. Thus, SSEP in combination with needle and stimulant electromyography may quantitatively assess the time course of changes in the spinal cord conductors at and beneath the lumbar enlargement of the spinal cord in the treatment of degenerative and dystrophic lumbosacral diseases.

Adult↗
PubMedDate not supplied

[Evaluation of the capacities of neurophysiological intraoperative monitoring in reconstructive surgery on the vertebral column].

AIM: To evaluate the capacities of neurosurgical intraoperative monitoring of somatosensory evoked potentials (SSEP) in reconstructive operations on the vertebral column. MATERIALS AND METHODS: The Center of Spinal Surgery examined 30 patients treated in February to July 2001. According to the diagnosis, the distribution was as follows: degenerative diseases of the vertebral column (80%), its tumors (10%), injury (7%), and inflammatory diseases (3%). Of them, 13 (43.3%) patients underwent anterolateral decompression of the dural sac of roots, 17 (56.7%) had traditional decompression of the dural sac and roots from the posterior access. The study was carried out on an 8-channel electrophysiological Viking-IV system (Nicolet, USA). Intraoperative SSEP monitoring was made by the routine procedure. The amplitude and latent time of subcortical peaks (P31) were determined at surgery. Intraoperative SSEPs were classified as defined with the American Electroencephalographic Society. The changes in the basic parameters of SSEP were also divided into transient (under 30 minutes) and permanent (above 30 minutes). RESULTS: True positive responses (significant changes in intraoperative SSEPs and the presence of postoperative neurological disorders) were 3.3% (1 patient); false positive ones (significant changes in intraoperative SSEPs without postoperative neurological disorders) were 23.3% (7 patients). False negative responses (normal intraoperative SSEPs and the presence of postoperative neurological disorders) were absent. The findings indicate that new postoperative neurological disorders should not be expected in patients with the clinical picture of mild neurological disorders if they have transient changes in the basic parameters of SSEPs that last at least 30 minutes. At the same time a risk group includes patients with severe neurological disorders since in these patients, compensatory capacities are primarily decreased and intraoperative exposures may result in early spinal circulatory decompensation. More frequent (every 10 minutes) recording of intraoperative SSEPs is also recommended for this group of patients is complicated surgical manipulations. CONCLUSIONS: 1. Neurophysiological intraoperative monitoring yields additional information for surgeons during an operation. 2. During intraoperative monitoring of SSEPs, it is necessary to assess any changes in the latter as true and to immediately find possible causes of these changes. 3. In patients with revealed spondylogenic spinal circulatory disorders and severe neurological disorders, even short-term changes in SSEPs should be assessed with particular carefulness before surgery.

Adolescent↗
PubMedDate not supplied

[Biochemical criteria of the inflammatory process in spinal osteomyelitis].

Patterns of collagen metabolism were studied in 36 patients with hematogenic vertebral column osteomyelitis simultaneously with evaluation of C-reactive protein, haptoglobin and ceruloplasmin in blood and consideration of the clinico-morphological steps of the disease. Hyperhydroxyprolineuria proved to be a more informative evidence for inflammation in vertebral column as compared with the proteins of acute phase of inflammation importance of hydroxyproline measurement in biological fluids for evaluation of the osteomyelitis development was elevated as the inflammation activity decreased (which was estimated by content of the acute phase proteins).

Acute-Phase Proteins↗
PubMedDate not supplied

[Diagnosis and surgical treatment of radiculomedullary disorders in hematogenic osteomyelitis of the spine].

Radiculomedullary disorders were detected in 42 of 112 patients with hematogenic osteomyelitis of the spine. Cerebrospinal dynamic tests, pneumomyelotomography, and venospondylography were used for establishing the diagnosis of spinal cord compression. Reconstructive surgery of the spine included interventions on the vertebral bodies, vertebral canal, and meninges of the spinal cord. With the use of the elaborated methods satisfactory results of treatment were produced in 38 patients with hematogenic osteomyelitis of the spine and radiculomedullary disorders.

Adult↗