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Biomedical subjects

S Alusík

Publications and source records attributed to S Alusík.

At least 19 recordsLinked to original sources

[Geriatrization of internal medicine].

The author draws attention to the need of more profound knowledge of geriatrics in the training of specialists in internal medicine. He draws attention to the ageing population, trends in advanced countries and planned enlistment of general specialists in internal medicine into primary care.

Aged↗

[Minocycline in the treatment of rheumatoid arthritis].

The author presents a review of contemporary knowledge on the treatment of rheumatoid arthritis with minocycline. He analyzes the assumed mechanism of action, dosage and the most frequently encountered undesirable effects of treatment. He informs the reader on the results of the most important studies with minocycline.

Anti-Bacterial Agents↗

[Crouzon's syndrome, arthritis and crural ulcers].

The author describes a special inflammatory rheumatic disease in a 48-year-old female patient with Crouzon's syndrome which most probably could be included among seronegative spondarthritis. The author discusses the possible ratio of inborn disease in the atypical course of the rheumatic disease.

Arthritis↗

[Rheumatoid pericarditis: correlation with immunologic parameters].

In 35 patients with rheumatoid pericarditis the laboratory findings were compared with those of a group of 65 patients with rheumatoid arthritis without a pericardial exudate. The authors assessed the red cell sedimentation rate and serum levels of immunoglobulins G, M, A, semiquantitative values of the rheumatoid factor, circulating immunocomplexes, C3 and C4 complement components, the positivity of antinuclear antibodies and values of C-reactive protein. The authors found significantly elevated values of immunoglobulins M in patients with rheumatoid arthritis without a pericardial exudate. As regards the other investigated parameters the two compared groups did not differ.

Adult↗

[Fever of unknown origin].

From a total of 4,123 hospitalized patients the criteria of fever of unknown origin were met by 81 (2%) who were divided with regard to the evoking cause into five groups: infection, tumors, rheumatic diseases, other diseases, diagnosis not established. The most frequent cause of fever was infection (29 patients, i. e. 35.8%), rheumatic diseases (16 patients, i. e. 19.7%), and the group of other diseases (14 patients, i. e. 17.3%). Tumors as the cause of fever held the fourth place (12 patients, i. e. 14.8%). In a small group of patients (10, i.e. 12.3%) the diagnosis was not established.

Adult↗

[Anemia--the single symptom in celiac disease in adults].

The authors describe the case of a 21-year-old female patient where for several months anaemia was the only symptom of subsequently diagnosed coeliac disease. They draw attention to the possibility of a monosymptomatic course of coeliac disease and discuss similar observations reported in the literature.

Adult↗

[Adult-onset Still's disease--the effect of methylprednisolone pulse therapy].

The authors describe in a 40-year-old woman Still's disease with an adult onset. The activity of the disease was not controlled by large Prednisone doses and therefore pulsed treatment with methylprednisolone with very favourable results was used. The authors discuss the use of pulsed treatment with methylprednisolone in this disease.

Adult↗

[Cardiovascular manifestations of systemic lupus erythematosus].

The authors assessed the damage of the cardiovascular apparatus in a group of 57 patients with systemic lupus erythematosus. Arterial hypertension was recorded in 19 patients (33%). The other most frequent defects were damage of the pericardium in 12 patients (21%) incl. 8 (14%) who had a pericardial exudate. Ischaemic heart disease was recorded in six patients. Serious forms of vasculitis were recorded in three patients and haemodynamically significant aortal insufficiency in two patients. Other forms of cardiovascular damage were rare.

Adolescent↗

Agranulocytosis in a patient with primary Sjögren's syndrome.

The authors describe a case of primary Sjögren's syndrome, which was complicated with severe autoimmune agranulocytosis quite sensitive to immunosuppressive therapy. Agranulocytosis is a very rare complication of this autoimmune rheumatic disease as opposed to leucopenia. A remarkable feature of the presented case is the fact that correct diagnosis of primary Sjögren's syndrome has not been settled for almost 25 years. The disease has manifested only in the form of arthropathy imitating rheumatoid arthritis.

Agranulocytosis↗

Large arteries involvement in scleroderma--a case report.

The authors describe a thirty-nine-year-old woman patient presenting with progressive systemic sclerosis and an unusual angiographic picture of an impairment of large arteries, which in their opinion is due to the primary disease. The review literature reports about similar arterial involvement in scleroderma.

Adult↗

[The anticardiolipin syndrome after breast reconstruction].

In a 38-year-old patient 17 years previously silicone prostheses of both breasts were implanted. Three years after operation spontaneous abortions developed, later repeated venous and arterial thromboses. Laboratory examinations revealed antibodies against cardiolipin and the diagnosis of anticardiolipin syndrome was established. The authors discuss the relationship between the performed operation and the present disease.

Adult↗

[Aspects of treatment of hypertension in rheumatic diseases].

The author deals with the reasons of the frequent incidence of hypertension in rheumatic diseases and some special aspects of its therapy (nephrogenic hypertension in systemic diseases, weakening of the action of antihypertensive drugs by nonsteroidal antiinflammatory drugs, chronic corticosteroid treatment and the unsuitability of some antihypertensive drugs in different rheumatic diseases).

Humans↗