Significance of cortical-amygdalar-hypothalamic connections in retention of conditional taste aversion in rats.
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Biomedical subjects
Publications and source records attributed to S Azuma.
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Authors report a case of craniopharyngioma with hyperprolactinemia, which was never noticed before surgical operation and showed the amenorrhea-galactorrhea syndrome from 7 months after surgical procedure. The patient is a 44 years old housewife. By the medication of CB-154 (Bromocriptin), the high value of plasma prolactin came to normal range and the galactorrhea disappeared, but the amenorrhea persisted. Because author was able to except the possibility of combine of PRL releasing pituitary adenoma or ectopic malignant tumors from the various examination and laboratory findings, the mechanism of secretory disturbance of PRI inhibiting factor in hypothalamus was investigated. These are 1) compression or invasion to hypothalamus through the recurrence of residual tumor, 2) mechanical focal damage of hypothalamus due to surgical manipulation, 3) side effects in hypothalamus depended on postoperative radiation and 4) others. As first element is denied in findings of postoperative CT scan, author is considering that second and third element may be possible factor.
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We report a 69-year-old female patient with mucinous cystadenocarcinoma of the appendix and elevated serum carcinoembryonic antigen (CEA). Serum CEA levels were 27.6-37.8 ng/ml. An oval shaped cystic mass at the ileocecal region was consistently seen by several radiologic procedures such as, barium enema, ultrasonography, computed tomography, and magnetic resonance imaging. The tumor was resected, and the histopathologic findings indicated mucinous cystadenocarcinoma of the appendix. CEA was demonstrated in the neoplastic columnar cells in immunohistochemical studies. The literature on the determination of serum CEA level in adenocarcinoma of the appendix is reviewed.