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Biomedical subjects

S Bergmann

Publications and source records attributed to S Bergmann.

65 records · Page 4Linked to original sources

[Initial reports on experiences in working with special groups in child day care centers].

A decisive condition for advancement at an early stage is the detection of physical damage. In this connection the GDR Ministry of Public Health has published guidelines for the establishment of special groups for infants suffering from physical damage, at ordinary creches (Verfügungen und Mitteilungen 15/1976). In 1976/77 a total of eight special groups with 64 children were set up at creches in the city of Erfurt. The criteria for assigning children to such groups were age and the type/degree of damage, with the aim of having homogeneous group structures. Advancement was through an all-day teaching process, in which parents were involved by giving them guidance, inviting them for discussion evenings and calling on their homes. A description is given of the approach to teaching and methods and planning (written timetables for specific months, weeks and days), all of which are essential in creating adequate educational conditions taking into account individual differences in the level of performance and the prevailing primary damage (e.g. disablement, impaired hearing, marked milieu damage).

Brain Damage, Chronic↗

[Possibilities and limits for palsied children in the general polytechnical school (author's transl)].

Some children with cerebral palsy attend the ten-form general polytechnical school. To this end, several prerequisites have to be fulfilled and other essential arrangements to be developed in cooperation with specially trained teachers. The learning conditions have to be fitted to the improving abilities of children during the educational process. Factors of influence and cooperation modes are discussed.

Adolescent↗

Histomorphometric analysis of normal bone from the iliac crest.

Bone specimens from a standardized area of the iliac crest were obtained at autopsy in 105 individuals after sudden unexpected death and at biopsy in 30 living volunteers. Seven micron thick sections of the plastic embedded undecalcified material were produced and stained. The amount of cancellous and cortical bone and the parameters attached to description of bone remodelling were determined by point counting and simple measurements, in order to establish normal mean values and range in a Danish population. A decrease in the amount of bone, trabecular as well as cortical, was found with increasing age in both males and females. The extent, volume and width of osteoid seams and the osteoclastic resorption were found to be age-independent. The osteoclastic resorption in cortical bone in males decreased, however, with increasing age. The reported values are of the greatest importance for the use of histomorphometric analysis of bone biopsies as a diagnostic tool in metabolic bone diseases. It is stressed, however, that supplementary information of the dynamic aspects of the bone remodelling would be necessary for the understanding of the pathogenesis of bone changes. Such information might be obtained by using tetracyline double labelling.

Adolescent↗

Effect of age and arteriosclerosis on the response of Parkinsonian patients to levodopa.

Twenty-four patients with Parkinsonism were treated with levodopa for up to one year. Ten were aged under 65, 12 were aged 65 or over, and two were specifically included because they were considered to have arteriosclerotic Parkinsonism. These two patients showed no response to treatment. The 10 younger patients showed less clinical evidence of arteriosclerosis than the older ones, and responded significantly better to treatment with levodopa. Mean improvement was 61% in the younger group after 12 months' treatment and 28% in the older group. Improvement was greatest within three months of starting treatment. Abnormal movements which resulted from treatment with levodopa could be reduced with only slight loss of therapeutic benefit by the addition of tetrabenazine.

Age Factors↗

Incidence of side effects from levodopa during the introduction of treatment.

Twenty patients with Parkinsonism were investigated in order to establish whether the gradual introduction of treatment with levodopa allows a higher dose to be tolerated than can be achieved if treatment is introduced rapidly. No indication was obtained that slow introduction of treatment offers an advantage in maximum tolerated dose, and patients aged 65 and over responded similarly in this respect to those under 65. The maximum tolerated dose is slightly lower in the elderly patient. The incidence of the different side effects does not appear to be affected by the rate of increasing the dose of levodopa.

Aged↗

Dietary habits in Eastern Germany: changes after reunification and their relation to CHD risk profiles (DRECAN).

As part of the DREsden CArdiovascular risk and Nutrition study, 2038 participants, selected from a cohort of 3076 workers in the Dresden area, underwent a detailed nutritional analysis of the periods before and after German reunification. Although protein, fat, carbohydrate, and total calorie intake did not change in Dresden after reunification, polyunsaturated fat replaced 17% of the saturated fatty acids, dairy product intake tripled, and fruit intake increased by 70%. Relative to a reference PROCAM 'western' cohort, the 90th percentile of triglycerides was higher in middle-aged men, and the levels of total cholesterol and HDLC were higher in all males. Serum LDLC levels in males and females were similar. Serum lipid concentrations and the prevalence of hyperlipidemia were similar to those of the PROCAM cohort, but smoking was less common. In young males and females, body mass index was higher; hypertension was more frequent. We assume that the differences in nutrition and risk profile before reunification were less substantial than commonly believed.

Adult↗

[Comparative characteristics of plasma lipoproteins and mesenteric lymph in the rabbit: spectrum and chemical properties].

Rabbit mesenteric lymph contained all the main classes of lipoproteins detected in plasma: chylomicrons (CM), very low density lipoproteins (VLDL), low density lipoproteins (LDL), high density lipoproteins (HDL). The main classes of lipoproteins in lymph were CM and VLDL, whereas LDL and HDL were the main lipoproteins in blood plasma. The heaviest subfractions HDL3 were not observed in mesenteric lymph. Lymph contained only low amount of LDL; molecular mass of lymphatic LDL was lower as compared with the blood plasma lipoproteins. Mesenteric lymph lipoproteins were enriched with triglycerides and contained less cholesterol, phospholipids and protein than the corresponding blood plasma lipoproteins. As distinct from blood plasma lipoproteins, apo E and apoproteins of low molecular mass (apo C?) were not found in lymphatic lipoproteins. Content of Apo-I was much higher in lymphatic VLDL as compared with the blood plasma VLDL. The dissimilarity in patterns and composition between blood plasma and lymphatic lipoproteins indicated that the latter were derived from intestine. Thus, intestine was able to produce CM, VLDL, HDL2 and apparently a small amount of LDL.

Animals↗