Soft-tissue augmentation with Fascian.
For a century, under various implant circumstances, the propensity of pFGs to be replaced with host fibroblasts and collagen has been established. Harvested from screened human donors, Fascian is an injectable formulation of the same substance that is applicable for soft-tissue repair and augmentation. Provided in preloaded syringes, the material has many advantages over presently available substitutes. This freeze-dried material does not require refrigeration, and, because of low allergenicity, test implantation is not indicated. Because it is available in multiple particle sizes that can even pass through a 27-gauge needle, Fascian is suitable for fine defects, and because of the material's volume and density, lesions usually not considered for injectable augmentation may be treated with larger particles. The process of tissue particulation has not altered the inherent graft properties, and Fascian seems to evoke the same process of collagen replacement that routinely occurs in larger grafts.