Biomedical subjects

S C Vir

Publications and source records attributed to S C Vir.

24 records · Page 2Linked to original sources

PubMed1978

Vitamin C status of institutionalised and non-institutionalised aged.

The vitamin C status of 186 elderly subjects living at home and institutionalised in hospital, residential accommodation and sheltered dwelling was studied. Subjects from hospital and home receiving multivitamin supplements regularly were grouped separately. Ascorbic acid deficiency (plasma ascorbic acid less than or equal to 0.3 mg/100 ml) was noted in 47.2, 39.0, 46.2 and 47.4 per cent subjects of home, hospital, residential accommodation and sheltered dwelling, respectively. All subjects receiving multi-vitamin had plasma ascorbic acid (PAA) levels greater than or equal to 0.3 mg/100 ml. The mean levels of PAA appeared higher in females than males and the percentage incidence of low vitamin C status was higher in males than females in the majority of the groups. Leucocyte ascorbic acid (LAA) levels were measured in only 26 subjects of residential accommodation and of these 38.5 per cent had low LAA levels (less than 15 microgram/10(8) cells). The biochemical vitamin C deficiency was not accompanied by any recognised clinical manifestation.

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PubMed1978

Chromium status of the aged.

Plasma chromium levels in the aged ranged from 0.5--22.1 ng/ml and revealed no relationship with serum cholesterol or fasting blood glucose levels. Plasma chromium values showed no consistent relationship with age and were not affected by sex.

Age Factors↗

PubMed1977

Thiamine status of institutionalised and non-institutionalised aged.

Thiamine status of 196 institutionalised (in hospital, residential accommodation and sheltered dwelling) and non-institutionalised Caucasian aged subjects was assessed by combined dietary, biochemical and clinical studies. Fourteen subjects (7.1 per cent) consumed less than two-thirds of recommended vitamin B1/DAY. Erythrocyte transketolas activity coefficient (a) test indicated biochemical deficiency of thiamine in 17.6 per cent males and 12.5 per cent females. The incidence of deficiency was highest in subjects of sheltered dwelling. Multivitamin supplementation failed to raise the biochemical thiamine status to normal in 2.9 per cent subjects. No characteristic clinical features of thiamine deficiency were noted, though extreme loss of appetite was reported by 3 subject with activity coefficient greater than 1.30. Dietary intake was not always associated with deficient biochemical indices. The possible factors such as alcohol intake and low folate status affecting the biochemical status of thiamine are discussed.

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PubMed1977

Riboflavin status of institutionalised and non-institutionalised aged.

A combined dietary, biochemical and clinical study was carried out on 196 aged subjects residing at home and institutions (hospital, residential accommodation and sheltered dwelling) to evaluate the nutritional status of riboflavin and to assess the effect of regular vitamin supplementation. The dietary intake of vitamin B2 was below two-thirds of the recommended in 33.3 per cent males and 17l9 per cent females. Biochemical deficiency of riboflavin was noted in 7.1 per cent subjects by erythrocyte glutathione reductase (EGR) activity coefficient (AC) test. An association between activity coefficient and low intake was found when the coefficient was greater than or equal to 1.30. There was no significant correlation between activity coefficient and dietary vitamin B2/day or vitamin B2/100 g protein. Regular oral administration of multivitamin (containing 2.5 mg vitamin B2) prevented biochemical deficiency of the vitamin. Clinical signs of riboflavin deficiency were not seen except in one female subject of sheltered dwelling.

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PubMed1977

Vitamin B6 status of institutionalised and non-institutionalised aged.

The vitamin B6 status of 196 aged subjects living at home and institutionalised in hospital, residential accommodation and sheltered dwelling was studied. Subjects receiving multivitamins were grouped separately and the effect of regular vitamin supplementation on the vitamin B6 status was assessed. The mean dietary intake of vitamin B6 was less than 2 mg/day in all the groups. The biochemical deficiency, as evaluated by erythrocyte glutamic pyruvic transaminase (EGPT) index, was observed in 42.3 per cent of the total subjects; the highest incidence was in subjects of sheltered dwelling. Twenty per cent of the subjects receiving multivitamin also had deficient biochemical levels. Anaemia was noted in 1.3 per cent of the vitamin B6 deficient subjects. Clinical signs of deficiency were noted in one female subject of sheltered dwelling.

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PubMed1977

Nutritional evaluation of B groups of vitamins in institutionalised aged.

The nutritional consequences of institutionalisation of the aged are poorly defined apart from hospital admissions. Food intake has been measured and correlated with biochemical assessment of B group vitamin function. Results reveal the dietary intake of thiamine and riboflavin were barely adequate while pyridoxine was deficient in 90%. Enzyme function tests revealed deficiencies at cellular level in up to 60% of subjects. In view of the increasing numbers in the ageing population these trends in nutrition require further study.

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