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Biomedical subjects

S Cottin

Publications and source records attributed to S Cottin.

At least 37 records · Page 2Linked to original sources
PubMed1981

[Bone metastasis revealing a hepatoma. 13 cases].

The authors report a series of 13 cases of bony metastases leading to the discovery of a hepatoma. They were subjects of male sex, average age 64 years. Nine were severe alcoholics. The presenting symptoms were in 7 cases neurological, in four cases an isolated bone tumour, finally, one spontaneous fracture, and one case with pain alone. Severe loss of weight was frequent; in 10 cases out of 13 it was greater than 5 kg. Hepatomegaly was found in 8 cases, but in 3 cases there was no sign suggesting liver disease. In 7 cases out of nine, the metastases were already numerous at the time of diagnosis. The diagnosis of metastases from a hepatoma was made on the bone histology 11 times and from the hepatic histology in 6 cases. The histological of the bone metastasis reproduces very well that of the liver. In four cases there was local secretion of bile, in one case the metastatic liver cells underwent steatonecrosis.

Adult↗
PubMed1980

[Pseudo-spondylodiscitis as manifestation of diffuse articular chondrocalcinosis (author's transl)].

Articular chondrocalcinosis (ACC), which is due to the precipitation of calcium pyrophosphate microcrystals, is known to produce symptom of acute arthritis or chronic degenerative polyarticular lesions. It is more rarely responsible for rapidly destructive lesions of the joints suggesting a metabolic or neurological process. The case reported here of a 66 year old woman with major lesions of the L1-L2 intervertebral space, together with other cases already published, shows that the destructive spinal forms of ACC may also present as subacute spondylodiscitis. The latter, however, merely represents 4.9% of all destructive articular lesions of ACC and 5.2% of the vertebral localizations of all forms of the disease.

Aged↗
PubMed1980

[Tricho-rhino-phalangeal syndrome. Four family cases].

The tricho-rhino-phalangeal syndrome was described in 1966 by Giedion. It is a hereditary disease with a dominant autosomic transmission. The authors describe a family with 7 cases, 4 of which were thoroughly studied. No chromosomic or biochemical error is known. However, x-rays of a young man in this family led us to classify this anomaly among the minor epiphyseal dysplasias related to the peripheral dysostosis of Braislford and clearly distinct Thieman's disease acquired by manual labor.

Abnormalities, Multiple↗
PubMed1976

[Intermittent rheumatism revealing a familial syndrome. Arthritis--urticarian eruptions--deafness: Muckle-Wells syndrome without kidney amylosis].

At a consultation with a 31-year-old man, motivated by painful episodes of joint pain that had started considerably earlier, a familial disease entity was discovered that included the three clinical signs of the Muckle and Wells syndrome : urticarial eruption, intermittent pain in the limbs originating in the joints, and bilateral deafness of perception. In spite of the absnece of renal amylosis, the similarity of the characteristics of these three elements, as well as the nature of the biochemical disturbances, and the mode of transmission, led the authors to consider these observations in the contest of this syndrome. The joint manifestations being indicative, the signs of this intermittent rheumatism are described, as well as the characteristics of the other disorders.

Adult↗