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Biomedical subjects

S Cottin

Publications and source records attributed to S Cottin.

At least 55 records · Page 3Linked to original sources
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Phenotypic heterogeneity of Pseudomonas syringae van Hall.

The study of phenotypic properties of 108 strains of Pseudomonas syringae pv. syringae van Hall isolated from Cherry laurel (50 strains) and various host plants (58 strains) and 53 strains of other pathovars of P. syringae and fluorescent Pseudomonas showed that the majority of the strains (91/108) were clustered in one phenon (phenon 14) containing strains commonly considered as P.s. pv. syringae. The present type strain of P.s. pv. syringae was distantly related to phenon 14. Other pathovars of P. syringae constituted 13 discrete phenons.

In Vitro Techniques↗
PubMedDate not supplied

[Paraneoplastic dermatopolymyositis].

In a retrospective study covering 11 years, 59 adult cases of dermatomyositis or polymyositis were reviewed. The disease was of paraneoplastic origin in 9 cases (15,25 p. 100), the same proportion as that found in the literature (14,6 p.100). The striking female predominance (8/9 cases) and the patients' mean age (61.11 years) were higher than those noted in non-paraneoplastic dermato- and polymyositis in adults (female predominance 34/50, mean age 52.9 years). Clinically, out of 9 patients 7 had dermatomyositis and 2 had polymyositis. The disease was discovered at the same time as the neoplasia in 7 of the 9 cases. Muscle histology showed that in contrast with non-paraneoplastic cases of dermatomyositis-polymyositis those of paraneoplastic origin had moderate lesions without fibrosis.

Aged↗
PubMedDate not supplied

[Limitations of normal eosinophilia or possible influence of nonsteroidal anti-inflammatory agents].

Statistical analysis of eosinophilia of 331 patients at the onset of hospitalisation define a logarithmic standard population of 327 patients whose eosinophilia rates stand between 0 and 810/mm3, among them 24 lies between 500 and 810, and 4 whose eosinophilia rise over 1,000/mm3. These 4 patients had transient hypereosinophilia whose etiology was defined only in 2 cases. The 24 patients with eosinophilia between 500 and 810/mm3 were significantly more frequently men, with rheumatoid disease (specially sciatica) and users of non steroidal antiinflammatory drugs (NSAID) than the general population. It suggest that NSAID may rise eosinophilia rates inside normal limits.

Adult↗
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[Evaluation of drug consumption by hospitalized patients. Prospective survey].

Drug use was assessed in a prospective 6-month study carried out in the Department of General Medicine V and Rheumatology of the Nantes Regional Hospital Center. An attempt was made to evaluate consumption as realistically as possible, and a judgment was made based on the consensus of the medical team as to whether the prescription was justified or not. The mean number of drugs consumed by each patient was 2.8; 60% being prescribed for cardiovascular and neuropsychiatric purposes. As 33% of the prescriptions were considered unnecessary, it would appear that use was excessive in these hospitalized patients.

Aged↗
PubMedDate not supplied

[Iatrogenic disease. Prospective study, relation to drug consumption].

The role of drug use in iatrogenic pathology was studied prospectively in a hospital department. It wa s found that patients received an average of 2.8 drugs and that 30% of the prescriptions were unnecessary. During this six-month study of all patients admitted to a general medicine and rheumatology department, there were 67 iatrogenic accidents affecting 12.3% of the population: 41.8% of the accidents were directly responsible for hospitalization, 35.4% were due to therapy initiated during hospitalization and 32.8% occurred during the hospital stay but were the result of earlier treatment. Moreover, 26% of the accidents were related to what was considered to be unnecessary therapeutics. This study shows that elevated iatrogenic pathology was due to excessive drug use. However, the degree of severity of the adverse effects varied considerably, and some could have been easily avoided.

Aged↗