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Biomedical subjects

S E Adam

Publications and source records attributed to S E Adam.

At least 109 records · Page 6Linked to original sources
PubMed1976

Susceptibility of desert sheep to infection with Schistosoma mansoni of Northern Sudan.

Each of two Desert Sheep was infected with 1500 cercariae of Schistosoma mansoni of Northern Sudan. Signs of infection were anorexia, soft faces, progressive weakness and loss of wool. The sheep were killed 254 and 269 days after infection. The findings were heavy infiltration of the lamina propria with inflammatory cells, numerous ova in the submucosa, hyperplasia of lymphoid tissue, oedema of the mesenteric lymph nodes, and focal pulmonary oedema and congestion. There were egg granulomas, focal necrosis, schistosomal pigment, fatty change, depletion of glycogen and reduction in the activity of adenosine triphosphatase, succinic tetrazolium reductase and glucose-6-phosphatase in the liver. In one sheep 1330 cercariae penetrated and 700 matured to produce males and females in a 5:2 ratio. In the other sheep, about one third of the cercariae penetrated and matured. The ratio of males to females was 3:1.

Animals↗
PubMed1975

Toxicity of Jatropha cucurcas for goats.

Eleven Nubian goats were fed with Jatropha curcas seeds at doses ranging from 0.25 g to 10g/kg/day. All dose levels were found to be toxic with fatal conswquences within 2 to 21 days. Liver biopsy samples taken 2 days after the start of feeding and subsequent biopsies showed congestion, varying degrees of fatty change, considerable reduction in glycogen content and necrosis of the hepatocytes. Lack of appetite, reduced water consumption, diarrhoea, dehydration, sunken eyes and a steadily deteriorating condition were important clinical signs of Jatropha intoxication goats. In all animals there was a decrease in the level of glucose and a marked rise in the concentration of arginase and glutamate oxaloacetate transminase (GOT) in the serum. Post-mortem examination revealed haemorrhage in the rumen, reticulum, kidney, spleen and heart, catarrhal or haemorrhagic abomasitis and enteritis, congestion and oedema of the lung and excessive fluid in serous cavities.

Alanine Transaminase↗
PubMedDate not supplied

The toxicity of Temik (aldicarb) in Nubian goats.

Single oral dosages of Temik (aldicarb 15%) given to Nubian goats at 150, 37.5 and 5 mg/kg caused toxic manifestations and death 5-180 min after administration. Daily dosing of the compound at 0.5 and 0.1 mg/kg caused death of goats between days 5 and 40. Death was preceded by clinical illness in which signs suggesting nervous system dysfunction consistently occurred. Pathological, haematological and biochemical changes are described.

Aldicarb↗