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S Friis

Publications and source records attributed to S Friis.

115 records · Page 7Linked to original sources
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The detection of panic disorder in chest pain patients.

The aims of this study were to 1) develop a detection model for recognizing panic disorder (PD), 2) develop a simple questionnaire as a screening instrument for PD detection, and 3) test in an outpatient cardiological chest pain population a detection model for panic disorder previously described by Fleet et al. [20]. Logistic regression analysis was performed to explore factors predictive of panic disorder and to test the cross-cardiological setting constancy of the Fleet model in 199 chest pain patients without previously known heart disease referred to cardiological outpatient investigation of chest pain. The SCL-90 somatization subscale, Agoraphobia Cognitions Questionnaire, chest pain quality, pain localization, and age were the best predictors of the presence of panic disorder. This model correctly classified 78% of the subjects. The sum-score of a three-item questionnaire correctly classified 74% of the subjects, while the previously described model by Fleet et al. correctly classified 73% of the subjects. A detection model and a screening questionnaire are proposed to improve the recognition of PD in this chest pain population. This study partly supports the cross-setting validity of a previously described detection model.

Adult↗
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Tolerance to intensive exercise and high levels of lactate in panic disorder.

We wanted to test the tolerance of intensive exercise and corresponding high levels of lactate in patients with panic disorder. Thirty-five consecutive patients with DSM-III-R panic disorder completed submaximal tests, and 24 completed additional supramaximal exercise tests. All experienced high values of lactate during the supramaximal test (M = 10.7 mmol/L, SD = 2.9), but only 1 patient experienced a panic attack. The blood lactate values in the present study were higher than the usually achieved values of 5 to 6 mmol/L during infusion. In general, 67% of patients panic during infusion, compared to 4% in the present study. This discrepancy in frequency of panic following exposure to endogenous and exogenous lactate is discussed on the basis of various hypotheses of panic disorder, with an emphasis on cognitive theory of panic. The study indicates that patients with panic disorder can safely undergo vigorous exercise of such intensity to result in significant lactate production, with the chances of panic being small.

Adult↗
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Comparing Personality Diagnostic questionnaire-4+ with Longitudinal, Expert, All Data (LEAD) standard diagnoses in a sample with a high prevalence of axis I and axis II disorders.

A comparison between the Personality Diagnostic Questionnaire-4+ (PDQ-4+) and Longitudinal, Expert, All Data (LEAD) standard diagnoses was made in a sample of 100 patients with a high prevalence of both axis I and axis II disorders. The internal consistency was considered acceptable (alpha >.70) for 3 of 12 PDQ-4+ scales. Diagnostic agreement between the assessment methods was poor for specific personality disorders (PDs). The PDQ-4+ gave many false-positive diagnoses. Changing the diagnostic thresholds only marginally increased the agreement between methods or the diagnostic efficiency of the PDQ-4+. Multiple regression analyses showed that the discrepancies between the methods were strongly associated with the current level of perceived symptoms (SCL-90-R).

Adult↗
PubMedDate not supplied

Syphilis and the risk of penis cancer.

BACKGROUND AND OBJECTIVES: Until recently, syphilis was considered a major cause of penis cancer. The possible role of syphilis was discarded without much debate with the detection of certain of human papillomaviruses centrally involved in the etiology of penis cancer. GOALS: To reevaluate the association between syphilis and penis cancer by using truly population-based cancer and syphilis data and to generate a more sound basis for judging the possible role of syphilis in the etiology of penis cancer. STUDY DESIGN: Patients with epidermoid cancer of the penis, totalling 1,523, were diagnosed and reported to the Danish Cancer Registry from 1943 to 1990. Through linkage with the Danish Syphilis Registry, the impact of prior syphilis infection was evaluated in a case-control design using patients with colon cancer or stomach cancer as controls. RESULTS: Depending on the criteria used to assess prior syphilis status, 3% to 5% of patients with penis cancer had had syphilis before the cancer diagnosis. The corresponding proportions were 2% to 4% among patients with colon cancer and 2% to 5% among patients with stomach cancer. Logistic regression showed that patients with penis cancer did not have a syphilis history significantly more often than control cancer patients. CONCLUSION: Syphilis should be removed from the list of possible causes of penis cancer.

Adult↗
PubMedDate not supplied

Personality profiles in patients referred for chest pain. Investigation with emphasis on panic disorder patients.

Patients (N = 199) referred to cardiac outpatient investigation because of chest pain were assessed with the Personality Diagnostic Questionnaire (PDQ-4). Thirty-nine percent scored positive for any personality disorder. Borderline and avoidant personality disorders were found significantly more often in patients with panic disorder (PD) (n = 72) than in patients without PD (12.5% vs. 2.5%, 23.7% vs. 7.7%, respectively). In PD patients, the presence of any personality disorder was significantly associated with higher scores of self-reported anxiety-agoraphobia symptoms, neuroticism, and the presence of suicidal thoughts. These results suggest that personality pathology is important in a subgroup of patients presenting with chest pain and that these patients may require more extensive treatment.

Adolescent↗
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Why are the results of milieu therapy for schizophrenic patients contradictory? An analysis based on four empirical studies.

The results of milieu therapy with psychotic patients have been highly conflicting because of unrecognized differences among the wards investigated. Our own research indicates that for psychotic patients in short- and intermediate-term wards: A beneficial milieu has a low perceived level of anger and aggression and a high level of support, practical orientation, and order and organization. Confronting group therapy is detrimental and individually oriented milieu therapy beneficial. Community groups may become anti-therapeutic pseudo-groups. Extensive use of confrontational groups may contribute to a detrimental ward atmosphere. A high mean age of patients may contribute to a favorable low level of aggression. A high percentage of psychotic patients, a high number of patients, and a high staff turnover may lead to a detrimental atmosphere. On this basis we tried to change the milieu on a 26-bed therapeutic community ward which proved to have pseudo-groups and a detrimental ward atmosphere. The amount of compulsory group activities was reduced, the groups made more task-oriented, the amount of individually oriented milieu therapy increased, and the number of beds reduced. At re-evaluation the ward atmosphere had improved considerably.

Age Factors↗