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Biomedical subjects

S H Zaidi

Publications and source records attributed to S H Zaidi.

At least 37 records · Page 2Linked to original sources

Anthropological study of the mastoid air cell system in Pakistani races.

This is an anthropological study of the development of the mastoid process in the four ethnic groups of Pakistani races: Turko-Iranian, Indo-Aryan, Scytho-Dravidian, and Aryo-Dravidian. Cephalometric studies have established that the majority of Pakistanis are brachio to ultra-brachiocephalic (Cephalic Index 82-x). Radiological evaluation of normal mastoids and their planimetric measurements show that the mastoid process is smaller (Av: 10.24 sq.cm. +/- 0.8) than the Caucasian Western races (Av: 12-15 sq.cm.). Neither combined approach tympanoplasty, nor mastoid obliteration technique may be required, nor technically possible in a small mastoid. Natural epithelization of a small 'peanut size' mastoidectomy cavity does not justify these procedures. A modified radical mastoidectomy and tympanoplasty reconstruction provides a satisfactory result in chronic discharging ears.

Adolescent↗

Assessment of occupational benzene exposure in petrol filling stations at Rangoon.

An occupational health survey was conducted on workers, who inhale petrol fumes which contain low concentrations of benzene, at petrol filling stations in the city of Rangoon, Burma. To evaluate the exposure to benzene, urinary phenol (which is a principal metabolite of absorbed benzene) was measured in workers at petrol filling stations and in a control group of healthy male adults. The survey revealed that the urinary phenol content of workers exposed to petrol fumes was significantly higher than that of workers who were not exposed.

Adult↗

Noise levels and the sources of noise pollution in Karachi.

The menace of noise is a by-product of civilization and its hazards are well known. Noise levels were measured in Karachi, at different places and at different times of the night and day, using an Amplaid noise meter. The leg for Karachi came to 80 dB (A), the General Noise Index x (G.N.I.) to 460, and the noise pollution level (N.P.L.) to 99 dB (A). These values are significantly higher (P less than 0.01) than the available international data. The sources of noise production were indentified as, the road traffic, human activity, industrial and civil works, mechanical and engineering workshops. The most noticeable sources of noise pollution in Karachi, are the autorickshaws, trail motor bikes and the fag horns of public transport (JPMA 39-62, 1989).

Environmental Pollutants↗

Variations in the shape of foramen magnum in Indian skulls.

200 skulls from anthropology museum of GSVM Medical College, Kanpur, U.P., India, were studied to note the variations in the shape of foramen magnum. Foramen magnum was found to be variable in shape: Shapes noted were oval (64%), hexagonal (24.5%), pentagonal (7.5%), irregular (3.5%) and round (0.5%). The findings are hitherto not reported.

Foramen Magnum↗

Spirometry and flow-volume curves in healthy, normal Pakistanis.

Previous studies have indicated that lung volumes in healthy, normal Pakistani adults are smaller than measurements reported in comparable healthy European populations; in order to confirm these findings and to examine the relationship of maximal expiratory flow rates to lung volumes, we studied 250 non-smoking healthy subjects (116 men and 114 women) between the ages of 18 and 65 years. The population sample was drawn from urban and rural areas of Pakistan, with low levels of air pollution. The results indicate that the forced vital capacity (FVC) and forced expired volume in 1 second (FEV1) were lower in the Pakistani population compared to European populations and North American populations of European descent. These data are in conformity with previous studies; however, in Pakistani men the effects of age on FVC and FEV1 were slight so that, after the fourth decade, the FVC and FEV1 values are very comparable between the European and Pakistani populations. Amongst Pakistani women, on the other hand, FVC and FEV1 remained lower than in their European counterparts throughout adult life. Maximal expiratory flow rates amongst the men did not correlate with age, and these values were very similar to those reported in age-matched European populations. In women, however, there was a significant correlation of maximal flow rates with age and height, and the maximal expiratory flows were decreased compared to European populations. These data indicate that in Pakistani men pulmonary mechanics may be different to their European counterparts, allowing for higher maximal expiratory flows at any given lung volume.

Adolescent↗

Bhopal and after.

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Accidents, Occupational↗

Experimental bagassosis: role of infection.

The pathological lesions of bagassosis have been reproduced in guinea pigs given bagasse fibers along with low doses of actinomycete spores. In the early stages, interstitial infiltration with lymphocytes and macrophages as seen in humans was noted. Later, small interstitial bagasse granulomas composed of foreign body giant cells, fibroblasts, and lymphocytes developed, some of which had a laminated appearance. Lymph node changes consistent with an immunological reaction were observed. Actinomycetes alone showed occasional areas of pneumonitis and bagasse alone small granulomas consisting of foreign body giant cells and bagasse fibers. Finally, the combined effect of dust and actinomycetes produced interstitial fibrosis composed of thick reticulin fibers and occasional collagen fibers, which persisted to the end of the experiment. Bagasse alone and actinomycetes alone produced only thin reticulin fibers. It has been suggested that bagassosis is due to the synergistic action of bagasse fibers and Micropolyspora faeni and that in the pathogenesis of the syndrome an immunological component may be involved.

Actinomycetales Infections↗