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Biomedical subjects

S Joyston-Bechal

Publications and source records attributed to S Joyston-Bechal.

At least 37 records · Page 2Linked to original sources
PubMed1988

Clinical evaluation of plaque removal with a double-headed toothbrush.

A blind, two-way, crossover clinical trial, completed by 44 adult subjects, instructed in specific oral hygiene techniques, was carried out to compare the effectiveness of plaque removal between a new Scandinavian double-headed toothbrush and a popular single-headed brush, each used for one week. The results showed that the double-headed brush was significantly more effective in removing plaque overall than a conventional brush. The effect was most evident on all lingual surfaces, especially in the lower arch and molar regions. It was also particularly pronounced when the double-headed toothbrush was allocated for use in the 2nd week of the study. There was no significant difference in the cleaning ability of the 2 brushes on the buccal surfaces of the teeth.

Adolescent↗
PubMed1986

A follow-up study 3 years after metronidazole therapy for chronic periodontal disease.

In a previous study, a double-blind between subject comparison of the effects of metronidazole and placebo tablets was completed over 22 weeks in 45 subjects with chronic periodontal disease ranging in severity from moderate (PI = 2.0-3.9) to high (PI = 4.0-6.0). The results showed a significantly greater reduction in the mean probing depth of pockets with the use of metronidazole, but this reduction was apparent only in subjects with severe periodontal disease (PI = 4.0-6.0). 3 years later, 28 subjects attended. All groups still showed statistically significant improvements in all parameters when compared with those at the first visit. However, when compared with those at the end of the trial, there were statistically significant increases in gingival bleeding and calculus scores. An increase in plaque levels was also observed but this was not statistically significant. When subjects with moderate and severe periodontal disease were grouped together, there were no significant differences in any of the parameters between test and control groups. Moreover, the significantly greater reductions in mean probing depth of pockets, achieved with the use of metronidazole in the severe group at the end of the trial, had disappeared after 3 years. However, in subjects with mild disease, statistically significant reductions in pocket probing depth, not originally apparent, were observed 3 years later.

Chronic Disease↗
PubMed1984

Effect of metronidazole on chronic periodontal disease in subjects using a topically applied chlorhexidine gel.

A double blind between subject comparison of the effect of metronidazole and placebo tablets was completed over 22 weeks in 45 subjects with chronic periodontal disease ranging in severity from moderate (PI = 2.0-3.9) to high (PI = 4.0-6.0). All subjects used a topically applied chlorhexidine gel for the first 10 weeks. Throughout the trial plaque, bleeding and calculus were assessed on the buccal, lingual, mesial and distal surfaces of teeth 16, 21, 24, 36, 41 and 44 and their supporting tissues. The pocket depths on the same 4 aspects of all teeth present were measured. The regime employed consisted of oral hygiene instruction (OHI) at the initial visit followed by scaling and further OHI at visits 1 and 2 weeks later. After the third visit 16 X 200 mg metronidazole or placebo tablets were issued with instructions to take 1 that evening and 3 per day at 5-h intervals for the next 5 days. 4 weeks later, scaling and OHI were carried out and the course of test or placebo tablets was repeated. The subjects returned for further scaling and OHI 4 weeks later and the chlorhexidine gel was withdrawn. Final assessments were made 12 weeks later. The results showed that metronidazole had no effect on plaque levels and gingival bleeding beyond the effect of OHI, scaling and chlorhexidine gel. On the other hand, significantly greater reductions in pocket depths were achieved with the use of metronidazole. A surprising and interesting finding was that these reductions were apparent only in the subjects with severe periodontal disease (PI = 4.0-6.0).

Administration, Topical↗