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Biomedical subjects

S Kay

Publications and source records attributed to S Kay.

At least 145 records · Page 8Linked to original sources
PubMed1977

Nine year follow-up of a case of benign liver cell adenoma related to oral contraceptives.

The case of a 26-year-old women on oral contraceptives who developed a benign liver cell adenoma that was successfully resected is reported. She continued on her oral medication and developed a recurrence 3 years later. On her second laparotomy, the liver tumor was merely biopsied and not removed. Oral contraceptive use was continued for an additional 3 years and then stopped. The tumor has regressed and is no longer palpable or diagnosable. The patient continues to be well 9 years following her first surgical procedure.

Adult↗
PubMed1977

Sclerosing hemangioma of the lung: an endothelial or epithelial neoplasm?

The ultrastructural features of a sclerosing hemangioma of the lung in a 34 year old woman are described. The basic cellular response is thought to be endothelial and not epithelial. These conclusions are based on the finding of Weibel-Palade bodies within the tumor cells in addition to other characteristics generally associated with endothelial cells.

Adult↗
PubMed1977

Morphologic aspects of nuclear bodies in a case of bronchiolar-alveolar carcinoma of the lung.

The ultrastructural features of a bronchiolar-alveolar carcinoma of the lung are described wherein the presence of nuclear bodies in many of the tumor cells were noted. Although these bodies are not viral elements, it is surmised that they may be virus associated and consequently possibly related to the etiology of this tumor. A review of the ultrastructural findings in the pulmonary adenomatosis of sheep is presented, and these are compared with those in human disease. Experimental evidence of an infectious agent responsible for human lung carcinomas is discussed, and possible avenues for future investigation are delineated.

Adenocarcinoma, Bronchiolo-Alveolar↗
PubMed1977

Pathogenesis and treatment of plunging ranulas.

Three patients with plunging ranula, two of which occurred spontaneously and one of which followed removal of the submandibular gland, were treated by excision of the sublingual gland. The sublingual gland is removed through the mouth or through a cervical submandibular incision. No dissection of the cervical ramifications associated with the ranula is undertaken, and these disappear once the source of the extravasating saliva has been removed. Results of considerable experimental work reported by others, support the concept that plunging ranulas are extravasations of saliva from the sublingual glands.

Adolescent↗
PubMed1976

Carcinoma of the gallbladder: staging, treatment, and prognosis.

Sixty-six cases of carcinoma of the gallbladder treated at The Memorial Hospital, Danville, Virginia, and the Medical College of Virginia, Richmond, were staged according to depth of invasion and spread and graded histologically; the findings were correlated with survival. Results from the two hospitals were essentially identical and the survival figures correlated well with 399 reported cases in the medical literature which could be staged according to the depth of invasion. A simple method combining staging and histologic grading of cancer of the gallbladder, which can easily be applied to all cancers of the gallbladder removed surgically and which should prove useful in the management of this disease, is described. Essentially all of the carcinomas of the gallbladder in the series were incidental findings at surgery for gall stones which may explain a relatively high proportion of superficial carcinomas which are cured by the removal of the gallbladder.

Gallbladder Neoplasms↗
PubMed1976

Pulmonary blastoma: A light and electron microscopic study.

A case of pulmonary blastoma studied with the electron microscope showed two distinct cell types, i.e., epithelial and mesenchymal elements. The former demonstrates the differentiation toward ciliated bronchial cells, and the latter, cartilage. In view of these findings, coupled with the current understanding of pulmonary morphogenesis, the pulmonary blastoma is more likely to be a carcinosarcoma than a true blastoma. However, the separation between pulmonary blastoma as usually employed and the so-called pulmonary carcinosarcoma seems to be desirable because of different clinicopathologic features.

Adult↗
PubMed1976

Ultrastructural observations on a follicular carcinoma of the thyroid gland.

Electron microscopic studies were performed on a follicular carcinoma removed from a 31-year-old woman. The tumor was poorly differentiated and inoperable but distinctly follicular in pattern. Ultrastructurally, the neoplasm had many of the features of papillary carcinoma, follicular adenoma, and anaplastic carcinoma. Due to the presence of secretory granules it even somewhat resembled medullary carcinoma, but the granules were distinctly larger, and the production of amyloid was definitely excluded.

Adenocarcinoma↗
PubMed1976

Small-cell carcinoma of the male mammary gland. A tumor resembling infiltrating lobular carcinoma.

The cases of two patients with infiltrating lobular carcinoma of the male mammary gland are discussed. They represent two of a total of 16 male patients with mammary carcinomas examined at the Medical College of Virginia between 1950 and 1975. Two previous similar cases have been reported in the literature as "small-cell" carcinoma. In one of the current cases there is unexplained benign lobular proliferation with atypical features suggesting lobular origin of the infiltrating tumor.

Aged↗
PubMed1976

Primary pulmonary neurilemoma. Report of a case with ultrastructural examination.

The electron microscopic features of a primary neurilemoma of the lung, a very rare neoplasm, were studied. Characteristic Schwann cells were present, with cytoplasm and elongated cytoplasmic processes coated with a basal lamina. The highly characteristic Luse bodies were also seen. We add electron microscopic corroboration to the previous tissue culture confirmation of this unusual benign pulmonary neoplasm.

Humans↗
PubMed1976

Rhabdomyoma of the heart: ultrastructural study of three cases.

The electron microscopic features of three primary cardiac rhabdomyomas were studied for the first time. Distinct striated muscle cells arranged in a disorderly fashion are described. The cases demonstrated a spectrum of possible myobibril differentiation with one case having only Z-bands and myosin filaments present while the other two had well formed thick and thin filaments with all of the bands present including Z, I, A, H, and M. Glycogen bodies, numerous mitochondria with tubular cristae, lipid deposits, and peculiar striated structures resembling zebra bodies were also seen. Desmonsomal attachments suggestive of Purkinje-type fibers were seen in all of the cases and were the only types seen in cases 2 and 3. In addition, intercalated discs characteristic of myocardial fibers were noted in case 1. This finding still leaves the exact histogenesis of the lesion uncertain although origin from two types of fibers is possible.

Heart Neoplasms↗