The course and outcome of pregnancy in women with epilepsy.
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Birth Injuries↗
Biomedical subjects
S L Bahna
Publications and source records attributed to S L Bahna.
The course and outcome of pregnancy in women with bronchial asthma.
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Asphyxia Neonatorum↗
New aspects of diagnosis of milk allergy in children.
In clinical practice at present, milk allergy may be suspected by medical history, skin testing, or RAST. None of these procedures has shown an optimal correlation with the result of challenge testing. The obvious need for better diagnostic tests has stimulated numerous attempts to improve the current tests and to develop new ones. The use of individual milk protein fractions for skin testing or RAST has not shown superiority over using whole cow's milk. Lymphoblast transformation and leukocyte inhibition factor production have shown low specificity. The few studies on neutrophil chemotactic activity have shown contradictory results. Morphometric and immunohistochemical studies of small intestinal biopsy specimens seem to be more suitable for research studies than for routine clinical practice. The reliability of in vitro tests on cultured intestinal epithelium remains to be verified and is far from being applicable in clinical practice. The diversity of immunologic mechanisms of milk allergy is largely responsible for the difficulty encountered in developing a highly reliable test in the diagnosis of various reactions to milk allergy.
Chemotaxis, Leukocyte↗
Factors determining development of allergy in infants.
For an infant to develop allergy (atopy), three main factors seem to be needed: genetic predisposition, allergen exposure, and contributory factors. The role of genetics seems to be mainly in transmitting a general atopic constitution and controlling the general IgE response. Together with environmental exposure, genetics possibly plays a role in determining the allergic shock organ and the specific offending allergen. Of the vast number of environmental allergens, food by far seems to be the major one in infancy, followed by indoor allergens then outdoor aeroallergens. Several intrinsic and extrinsic contributory factors can enhance the development of allergy, perpetuate its chronicity, or facilitate precipitation of symptoms. These factors can be immunologic defects, gastrointestinal diseases, infections, or nonspecific irritants such as tobacco smoke inhalation. Understanding all these factors is essential in formulating any program for allergy prevention in infants.
Age Factors↗