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Biomedical subjects

S M Stewart

Publications and source records attributed to S M Stewart.

At least 55 records · Page 3Linked to original sources
PubMed1982

Schizophrenic children's utilization of images and words in performance of cognitive tasks.

Hospitalized schizophrenic (N = 15) and nonschizophrenic (N = 18) youngsters were compared on measures of verbal and imagery development as well as on four paired-associate learning tasks involving combinations of word and picture stimuli pairs. The results showed the schizophrenic group to be similar to the controls on verbal and full-scale intelligence measures but significantly inferior on performance measures. The schizophrenic group also showed a general disadvantage in paired-associate learning, with a trend toward specific differential difficulty with words as stimulus items. Results suggest the presence of nondominant hemisphere deficit in the target group and also provide weak support for theories of dominant hemisphere dysfunction in schizophrenia.

Association Learning↗
PubMed1978

Exacerbations of chronic bronchitis: exogenous or endogenous infection?

Six male patients with chronic bronchitis, who were known previously to have excreted Streptococcus pneumoniae and/or Haemophilus influenzae, both at the times of exacerbations and during remission, were studied for 43 to 52 months. Sputum was examined fortnightly and at the time of exacerbations. Strains of Strep. pneumoniae were serotyped and those of Haemophilus species were typed by antibiograms along with other supporting methods. Sera collected before or at the time of an exacerbation and seven and 30 days afterwards were examined by complement fixation tests against respiratory viruses and Mycoplasma pneumoniae. In 18 out of 25 exacerbations there was evidence of a new type of Strep. pneumoniae and/or Haemophilus spp. or of a current virus infection, suggesting exogenous infection in the majority of these cases. There was a possible reason for failure to detect a new pathogen in three of the seven cases in which none was found. In five further exacerbations adequate investigation was not possible.

Aged↗
PubMed1975

Detection of tetracycline resistance in Streptococcus pneumoniae.

Bacteriological details are given of a patient with chronic purulent bronchitis, who was being followed up during a survey of relapse in chronic bronchitis. A strain of Streptococcus pneumoniae, serotype 10, was isolated from the sputum over a period of six months, followed by a type 47A strain and later a type 28 strain. The patient was receiving prophylactic treatment with tetracycline throughout. The type 10 strain was sensitive to tetracycline in vitro by both the disc diffusion and doubling dilution sensitivity tests and mice infected with this strain were protected by tetracycline. In contrast, both the type 47A and type 28 strains were sensitive by the disc diffusion technique, but showed a low degree of tetracycline resistance by the doubling dilution method; mice infected with both these strains were not protected by tetracycline.

Animals↗
PubMed1975

Mycoplasmas and 'diphtheroids' in rheumatoid arthritis.

The failure to isolate conventional mycoplasmas from 88 synovial membranes and 119 synovial fluids from patients with proven rheumatoid arthritis using a variety of culture media and techniques agrees with the results of recent workers and suggests that these organisms are unlikely to play a role in the aetiology of the disease. In contrast, 'diphtheroid' organisms were isolated from 27 to 30% of rheumatoid specimens, but not from cultures of non-rheumatoid material. A significantly higher incidence of raised agglutination titres to C. acnes and to a 'diptheroid' isolated from a patient with rheumatoid arthritis in sera from patients with rheumatoid arthritis supports the conclusion that these organisms are present in the joints in such patients, though their role in this disease has yet to be established.

Agglutination Tests↗
PubMed1969

Pilot study of factors associated with exacerbations in chronic bronchitis.

The factors associated with exacerbations of chronic bronchitis were investigated in a pilot study of 23 male patients over a period of 29 months. There were 63 exacerbations-56 were fully investigated and in seven only serological studies were possible. Evidence of the presence of an infective agent was sought in the early stages of the exacerbations and during relative quiescence. Significantly more potential pathogens, both bacterial (pneumococci and Haemophilus influenzae) and viral and mycoplasmal, were found during exacerbations than in quiescent periods. It was not possible to demonstrate that atmospheric pollution or low temperature influenced exacerbations, but the data are insufficient to exclude a small effect.It is emphasized that the value of future work on these lines would be increased if agreement could be reached on the definition of an exacerbation.

Adult↗