The relationship between the aetiology of pneumonia in adults and certain clinical and radiographic findings.
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Biomedical subjects
Publications and source records attributed to S M Stewart.
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We review our experience treating patients with medically refractory frontal sinusitis that could not be relieved with endoscopic intranasal surgery alone. Fourteen combined external and intranasal endoscopic frontal sinusotomies were performed on a consecutive sample of 11 patients presenting over a 38-month period of study. Postoperative results were classified as cured, improved, unchanged, or worse, based on patient symptoms and physical findings. At a mean postoperative follow-up of 19 months (range 4-36), 100% of these patients had benefited from this technique (7 cured, 4 improved, 0 unchanged, 0 worse). There were no major complications and natural sinus physiology was preserved. We conclude that a combined external and endoscopic intranasal frontal sinusotomy is an effective alternative to frontal sinus obliteration.
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Pathological characteristics of colorectal cancers and adenomas developing in 140 members of 34 Hereditary Non-Polyposis Colorectal Cancer (HNPCC) families are described. In addition the pathological features of six cancers and 47 adenomas obtained from 216 at risk subjects in colonoscopic surveillance programmes are given. Survival rates for Dukes A, B and C cancers were 90%, 76% and 50% respectively, but only 32% of cancers were Dukes C. This would support the view that HNPCC malignancies are relatively non-aggressive, despite there being an excess of poorly differentiated and mucinous tumours. There is circumstantial evidence that evolution of malignancy occurs through the adenoma - carcinoma sequence.