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Biomedical subjects

S Manzar

Publications and source records attributed to S Manzar.

At least 37 records · Page 2Linked to original sources

Neonatal resuscitation: a report from Oman.

There has been a considerable increase in the educational level and awareness of neonatal care in developing countries over last decade. The importance of neonatal resuscitation, however, has been ignored. This report discusses the importance of structured neonatal courses with emphasis on the need for more such courses at regional levels, especially in developing countries. The concept of basic and advanced life support of the newborn is also presented.

Humans↗

Delayed presentation of congenital diaphragmatic hernia in association with group B streptococcus infection in a preterm Omani neonate.

We present an interesting case of a preterm Omani newborn that had delayed onset of congenital diaphragmatic hernia in association with group B streptococcus infection. The association and the pathogenesis are supported by literature review. The message to follow is that any neonate with prolonged course of streptococcal pneumonia, with unusual course, should be investigated for presence of congenital diaphragmatic hernia.

Hernia, Diaphragmatic↗

Effect of labor duration on fetal fibrinolysis: a pilot study.

OBJECTIVE: Activation of neonatal and maternal fibrinolysis at birth has been shown earlier. To evaluate further on the effect of labor duration on the fetal fibrinolysis, we conducted this preliminary study. METHODS: An indirect assessment of activation of fetal fibrinolysis was carried out, by measuring the cord blood D-dimer. The cord blood samples were obtained randomly from 11 women undergoing vaginal delivery at term. Specimens were analyzed within 2 hours by using latex agglutination test. Pregnancy details were obtained from the delivery ward register. RESULTS: The mean duration of labor was noted to be 5.4 hours (3.5- 9.46). The mean maternal age was 25.5 years (21-34). The mean gravidity was 2.4 (1-5) and the mean parity was 1.4 (1-4). No effect of duration of labor on the cord blood D-dimer concentration was observed. CONCLUSION: Our findings suggested that it is not the time or duration of labor process that is involved in the activation of fetal fibrinolysis. The role of uterotropins and uterotonins (oxytocin, prostaglandins and endothelin-1), in activation of fetal fibrinolysis, should be evaluated in further studies.

Adult↗

Survival pattern among extreme preterm infants.

OBJECTIVE: To look at the survival pattern of extreme preterm Omani infants (23-26 weeks gestation) and compare it with the western countries. METHODS: All extreme preterm Omani infants (gestational age of 23 to 26 weeks) admitted from November 1991 to February 1998 at the Neonatal Intensive Care Unit of Sultan Qaboos University Hospital were reviewed. The detailed records of the infants, including name of mother, age, gravidity, parity, route of delivery, Apgar score, time of birth, inborn or outborn, birth weight, gestational age, sex, need for resuscitation, course in the Neonatal Intensive Care Unit, admission and discharge diagnosis, and outcome were collected from the register. The infants were stratified according to the gestational age and then analyzed for the survival rate among the different gestational ages. RESULTS: A total of 32 extreme preterm infants were admitted to the Neonatal Intensive Care Unit of Sultan Qaboos University Hospital from November 1991 to February 1998. The mean birth weight of the cohort was noted to be 798+123 gram (Range 480-1015 grams). The mean gestational age was noted to be 25.5+0.95 weeks (Range 23-26 weeks). An equal number of males and females were noted in the cohort, with male to female ratio of 1:1. A total of 13 infants survived out of 32 infants. The overall survival rate for the cohort was noted to be 41%. For the present study, the western statistics are averaged and than compared with the Omani statistics. The survival rate for western 26 week preterm infants was (on average) 61% as compared to 44% among Omani preterm infants. The same trend of low survival was noted for 23 and 24 week Omani infants, except for only one 25 week infant. CONCLUSION: The significant lower survival rate suggests the need for more attention and improvement in the management and care provided to the extreme preterm Omani infants.

Birth Weight↗