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S Mudd

Publications and source records attributed to S Mudd.

30 records · Page 2Linked to original sources
PubMed1967

Electron microscopy of the combination of antibodies with flagellar antigen and with a pyocine.

Micrographs are presented of antibodies in combination with flagella of Salmonella typhi and with a phage-bound pyocine Rmc, which is supposed to be the tail of a defective bacteriophage from Pseudomonas aeruginosa. The pyocine preparation seems to offer advantages for the study of antibody-antigen complexes. Under the conditions of our experiments, the surfaces of the antigenic structures are saturated with antibody layers approximately 95 A in thickness, i.e., slightly less than half the accepted lengths of 7S antibody molecules. Our interpretation is that the antibody is attached by combining sites at the ends of the molecules to form loops along the surface of the antigenic structures.

Animals↗
PubMed1966

Role of serum in the intracellular killing of staphylococci in rabbit monocytes.

Shayegani, Mehdi G. (U.S. Veterans Administration Hospital, Philadelphia, Pa.), and Stuart Mudd. Role of serum in the intracellular killing of staphylococci in rabbit monocytes. J. Bacteriol. 91:1393-1398. 1966.-Although some intracellular killing occurs in rabbit monocytes with heated normal serum or even in monocytes washed three times with Hanks' solution and with staphylococci not exposed to serum, efficient killing of coagulase-positive Staphylococcus aureus cells in the mononuclear phagocytes of rabbits is shown to require heat-labile components of serum. The effect of serum in promoting phagocytosis and intracellular killing may be exhibited either by presensitization of the staphylococcal cells before contact with leukocytes or by the presence of serum in the phagocytic system. Under any conditions studied the rate of intracellular killing of S. aureus is very slow.

Animals↗