Biomedical subjects
Publications and source records attributed to S Muroi.
A platelet kinetic study in 2 patients with acute promyelocytic leukemia (APL) associated with disseminated intravascular coagulation (DIC) demonstrated that the platelet survival was characteristically shortened. These findings suggest increased platelet consumption during the process of DIC in APL.
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Cycloscopy was performed in eyes with primary angle-closure glaucoma and non-glaucomatous wide-angle. In all eyes of primary angle-closure glaucoma, the ciliary processes were accessible through the small pupil by cycloscopy with minimal or no indentation. In fellow eyes of the previously acute-attack eyes, the ciliary processes were visualized through the small pupil without indentation. On the contrary, in primary angle-closure glaucoma eyes the significant shallow chamber depth was seen in 66%, and the positive prone-position test in 41%. The results obtained seem to suggest that morphological changes of the ciliary processes might be causally related to the manifestation of primary angle-closure glaucoma, and that cycloscopy is a reliable diagnostic method.
A new gonio-cycloscope that magnifies an object up to 1.5 times was designed to observe the ciliary process and chamber angle. As a result of aging, the ciliary process became hypertrophic and more branched with discoloration. Leakage of fluorescein from the ciliary process decreased as intraocular pressure artifically increased, stopping completely at 50 mm Hg or more. Water drinking accelerated fluorescein leakage, while oral glycerol diminished it.
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