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Biomedical subjects

S Nagel

Publications and source records attributed to S Nagel.

54 records · Page 3Linked to original sources
PubMed1983

A follow-up study on familial polyposis coli in black patients.

We have updated our experience concerning eight families (24 patients) with FPC, 11 of whom had FPC with carcinoma and 13, FPC only. The importance of biopsy to prove the presence of an adenoma (tubular, villous or tubulovillous) was emphasized. Although we prefer total colectomy with ileorectal anastomosis as definitive treatment, total proctocolectomy also has been recommended. The value of careful follow-up examination to detect carcinoma in the retained rectal segment and the periampullary region has been stressed. No racial differences were noted.

Adenocarcinoma↗
PubMed1975

[Results of chewing and ruminant activity of cows fed rations of cereal straw of various physical forms and after chemical treatment with sodium lye].

3 trials were conducted with adult cows. The animals received different types of coarse fodder (straw, lucerne) which was subjected to chemical treatment (liquid NaOH) and mechanical treatment (pelleting, wafering); then, the chewing and ruminating activity of the cows was measured. Different criteria were used, i.e. movements of the jaws during food intake and rumination and number of regurgitated bits of food. On the average, one movement of jaws lasted 0.94 sec. and swallowing and regurgitation took 5.5 sec. From this, the duration of the rumination process was determined. No differences in ruminating activity were found between lucerne and chopped/chaffed food while the the case of wheat straw about 30% of additional ruminating activity was performed in comparison with pelleted lucerne and chaffed food. This structural effect was even a bit more pro nounced when the straw was first ground and then wafered. Preceding chemical treatment of the straw with liquid NaOH reduced the ruminating activity in the case of chopped food by 53%, with pellets by 40% and with straw pressed into blocks by 62%. The finess of the feed was in no case found to be related to rumination activities, while hardness of the food particles as well as physical and chemical treatment of the food had an importent influence on the rumination activity.

Animal Nutritional Physiological Phenomena↗
PubMed1975

[Quantitative determination of chewing and rumination activities in dairy cows].

A device is described (RMBZ) which allows to register the movements of the lower jaws of cattle during food consumption and rumination. A microfeeler is connected to the device which is fastened to the halter. With the use of this device following data can be obtained separately: the total number of chewing movements; the number of bits of food swallowed and the length of chewing period in this way it has become possible to avoid the laborious and time-consuming work that is necessary to analyze strip charts. Trials were performed with varying patterns of food ration showing that this device is particularly suited for studies of this kind especially when compared with other devices using strip charts. Average deviations, e.g. in the number of rumination activities, from those registered with the recorder device were +/- 5%. The measuring technique and the operating principle of the RMBZ device are described in some detail.

Animal Feed↗
PubMedDate not supplied

The isolated perfused liver. a new model using autologous blood and porcine slaughterhouse organs.

INTRODUCTION: Current models of isolated and perfused livers are limited by nonphysiologic perfusates or the need for the use of high numbers of laboratory animals. The present study was performed in order to rectify these difficulties. METHODS: To establish a new isolated perfused liver model, a perfusion circuit was developed using normothermic, autologous hemoperfusion and organs obtained from a slaughterhouse. RESULTS: Stable organ function was maintained over 220 min. The organs displayed physiologic values for measured variables, including oxygen consumption which varied from 5.2+/-1.5 ml/min at 40 min to 5.2+/-2.4 ml/min at 220 min, and bile production (0.15-0.31 ml/min, respectively). DISCUSSION: The present studies demonstrate a new approach for experimental liver perfusion by combining the optimal perfusion medium of autologous blood and slaughterhouse organs as source material.

Alanine Transaminase↗