Biomedical subjects

S Parot

Publications and source records attributed to S Parot.

At least 19 recordsLinked to original sources

PubMed1984

Developmental changes in ventilation and breathing pattern in unanesthetized kittens.

Ventilation and the breathing pattern of 12 intact, unanesthetized, unrestrained kittens, were recorded at intervals from the second postnatal day to the end of the eighth month. Five of the animals were also studied at 12 months of age. Ventilation (VE) became stable by the 5th month, whereas body weight was still increasing. The relationship between tidal volume (VT) and breathing rate (BR) changed with age. During the 1st month, BR fell and VT increased, VE increasing slowly. From 1 to 5 months, BR remained nearly constant while VT increased. Finally, from 5 to 12 months, BR decreased slightly, VT increased slightly, and VE did not change. The results are compared with relevant data from the literature, especially those derived from interspecific analyses.

Aging↗

PubMed1982

Hypoxemia, hypercapnia, and breathing pattern in patients with chronic obstructive pulmonary disease.

The results of lung function tests (total and functional residual capacities, residual volume/total lung capacity ratio, forced expiratory volume in one second) breathing patterns and arterial PO2 and PCO2 were studied in 651 ambulatory male patients with chronic obstructive pulmonary disease, functionally and clinically stable. Function tests were only loosely correlated with gas tensions: abnormalities in mechanics and in gas exchange are not necessarily related. In patients matched for the degree of obstruction, the breathing pattern depended upon both PaO2 and PaCO2. Isolated hypoxemia was accompanied by increased respiratory frequency without any variation in tidal volume: this suggests that the chemoreceptive systems still responded to changes in PaO2. Isolated hypercapnia was accompanied by a decrease in tidal volume and an increase in respiratory frequency. Consequently, the dead space/tidal volume ratio increased, leading to a drop in alveolar ventilation and to CO2 retention.

Adult↗

PubMed1981

Some limitations in the use of normal value tables.

Analysis of raw data from 822 (224 women and 598 men) Caucasian healthy subjects with age ranging from 19 to 50 years leads to a multiple correlation coefficient equal to 0.75 between vital capacity and age, height and weight. In spite of this highly significant correlation coefficient, the predicting value of the regression equation is very poor: on the one hand, residual fluctuation is very important, on the other hand, because of the small intraindividual variability, "normal for the group' does not necessarily mean "normal for the individual'.

Adult↗

PubMed1980