[Choice of a morphological reference to evaluate energy consumption].
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Biomedical subjects
Publications and source records attributed to S Parot.
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151 ambulatory male patients with chronic obstructive pulmonary disease have been studied twice, at time intervals ranging from 2 to 36 months (average : 11), to determine the relationships between changes in lung function tests, pattern of breathing and arterial PCO2. This longitudinal analysis confirms the results of cross-sectional studies: variations in PaCO2 seem independent of the evolution of lung function tests (FEV1, VC, FEV1/VC, RV/TLC). Increases in PaCO2 are associated with a decrease in tidal volume and no change in respiratory frequency. These changes in breathing pattern result in a decreased minute ventilation and an increased VD/VT ratio.