Placenta previa: to rest in bed or not to rest, be normal or "play sick"?
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Biomedical subjects
Publications and source records attributed to S Semchyshyn.
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Forty-seven of 52 women with pregnancy-induced hypertension completed a protocol consisting of 4 gm of hydrocortisone given over 24 hours (1 gm every 8 hours). All patients' fetuses were less than 36 weeks' gestation and had an immature lecithin sphingomyelin ratio (less than 2). The hydrocortisone was given to reduce the incidence of respiratory distress syndrome. The admitting systolic blood pressure was 148.8 +/- 21.8 torr and diastolic was 105.6 +/- 18.9 torr. Blood pressure change was compared before, during, and after treatment. This study demonstrates no aggravating effect on maternal blood pressure even in severely hypertensive (blood pressure = 160/110 torr) patients.
Balloon catheter was used for pre-induction cervical priming and in order to enhance induction of labor in 51 patients. This procedure was found to be a safe and effective adjunct to induction of labor in patients with unripe cervices (mean Bishop score 3.4) with induction of labor to delivery time of 6.5 h.
Three cases of peripartum pulmonary edema associated with steroid administration are reported. Two patients developed antepartum pulmonary edema after receiving hydrocortisone to promote fetal lung maturity. The third patient developed pulmonary edema shortly after delivery and after having received glucocorticoids antepartum.
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Three term pregnancies occurred in two women who had had porcine xenografts implanted at various times prior to pregnancy. These grafts were associated with uncomplicated pregnancies since chronic anticoagulation therapy was not necessary.
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