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Biomedical subjects

S Semchyshyn

Publications and source records attributed to S Semchyshyn.

At least 37 records · Page 2Linked to original sources

Blood pressure response in hypertensive pregnancies treated with cortisol.

Thirty-two hypertensive gravidas were treated in the third trimester of pregnancy with intravenous cortisol to enhance fetal lung maturity before premature delivery. Blood pressure was measured throughout 24 hours of steroid therapy. No significant increase in maternal blood pressure occurred. Complications and precautions are discussed. Fear of steroid induced exacerbation of maternal hypertension is not a valid reason to withhold steroid therapy in hypertensive pregnancy.

Adolescent↗

Fitz-Hugh and Curtis syndrome.

A review of 124 patients treated for pelvic inflammatory disease revealed 15 cases of presumptive Fitz-Hugh and Curtis syndrome. During the same 12-month period three patients mistakenly thought to have gall bladder disease came to laparotomy, only to be found to have Fitz-Hugh and Curtis syndrome. The subtle presentation of the syndrome is discussed.

Adult↗

Ovarian hemorrhage due to anticoagulants.

Six cases of ovarian hemorrhage secondary to anticoagulant therapy are described. Cardiac valvular prostheses required the use of oral anticoagulants in four patients in this series; the other two suffered a pulmonary infarction secondary to thromboembolism and required sustained anticoagulant therapy. Pertinent data from 28 other case reports are reviewed. Awareness of this syndrome during child-bearing years, early recognition, and aggressive management should prevent a fatal outcome.

Adolescent↗

Effects of hydrocortisone on lecithin-sphingomyelin ratio.

An intravenous infusion of hydrocortisone succinate was given in four divided doses during a 24 hour period to 17 high-risk pregnant women to accelarate fetal pulmonary maturity. Amniocentesis was performed before and 48 to 72 hours after treatment in all 17 patients. Comparisons were made of lecithin/sphingomyelin (L/S) ratios before and after treatment. The L/S ratio rose in 12 or 17 cases and was not influenced by the type of severity of maternal disease. Neither lenght of rupture of the membranes nor gestational age at the time of treatment affected the change in L/S ratio. Pretreatment L/S ratios (1.21 +/- 0.435 S.D.) were found to have a statistically significant difference from posttreatment values.

Amniocentesis↗

Giant ovarian cyst in a dwarf.

The authors describe a case of giant mucinous cystadenoma in a dwarf. The cystadenoma weighed 32 kg, almost half the patient's normal weight, Such tumours are rare and are sometimes mistaken for ascites. They are usually benign, but care should be taken to remove them intact since malignant degeneration of mucinous cysts occurs in 5 to 15% of cases. Understanding of the possible complications allows for a favourable prognosis.

Aged↗

Infant survival following uterine rupture and complete abruptio placentae.

This report concerns a case of spontaneous rupture of the uterus through a previous cesarean scar with resulting complete abruptio placentae and extrusion of the fetus inside the intact membranes and the placenta into the peritoneal cavity. That the infant survived this dual insult is worthy of reporting.

Abruptio Placentae↗

Laparoscopy: is it replacing clinical acumen?

One thousand sixty-one laparoscopic procedures (80% for diagnostic indications and 20% for therapeutic indications) performed during a 51-month period were reviewed to assess the effectiveness of laparoscopy in improving clinical diagnosis and avoiding major surgery. The error in preoperative clinical assessment as compared to postlaparoscopic diagnosis was approximately 50%: disease was suspected more often than found. Pelvic inflammatory disease, endometriosis, and ovarian cyst were the entities most often confused. Tubal coagulation was the most common procedure performed for therapeutic reasons. The complication rate for all laparoscopies and associated procedures was 2.6%.

Adolescent↗

Abdominal pregnancy complicated by genital and renal tuberculosts and hemolytic anemia.

After a 10-year period of primary infertility, a patient presented with abdominal pregnancy. Known to have had previously treated genital tuberculosis, on admission she was found to have renal tuberculosis and autoimmune hemolytic anemia. After fetal death, laparotomy was performed and the fetus was removed. The patient's anemia responded well to steroid therapy and she was discharged on antituberculous triple therapy. The literature on hemolytic anemia in pregnancy and in association with tuberculosis, as well as on ectopic gestations, was reviewed.

Adult↗