Biomedical subjects
S Stoĭkov
Publications and source records attributed to S Stoĭkov.
[The use of the antibiotic cefoxitin (Mefoxin) in gynecological practice].
The aim of this presentation is to study the advantages and disadvantages of perioperative prophylaxis with the antibiotic Mefoxin against the classical postoperative antibiotic prophylaxis with penicillin and gentamicine, as well as to analyse the place of this antibiotic in modern treatment of different forms of pelvic inflammatory disease. The authors conclude that the qualities of Mefoxin (high resistant wide spectrum antibiotic, covering aerobes and anaerobes), make it an ideal antibiotic for perioperative prophylaxis in gynaecologic and oncologic surgery; the clinical effectiveness of Mefoxin in the treatment of inflammatory diseases of the female pelvis precludes the need for a combined parenteral antibiotic therapy.
[Methods for the laboratory diagnosis of chlamydial infections and their use in current practice].
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[Epidemiological studies of patients with genital chlamydiosis in Pleven District].
The authors aimed at conducting an epidemiological analysis of genital chlamydial infection among married couples with infertility problems, women with pelvic inflammatory disease and among patients with promiscuity and clinical symptoms of genital infection in the region of Pleven. They performed a prospective study for a six month period of time. 36 married couples with infertility problems and 66 patients with promiscuity were included in the study. The authors conclude that genital chlamydiosis is a widely spread sexually transmitted disease among a large group of patients. Poor personal hygiene, poor education, young age, some professions which are a predisposition to promiscuity increase the risk of sexually transmitted diseases.
[Struma ovarii--a rare tumor in gynecological practice].
The authors present four cases of struma ovarii, observed a period of five years (1990-1995) in the Chair of Gynaecology and Obstetrics--Pleven. The literature data concerning this interesting problem was discussed in detail.
[A single-stage 2-layer suture in cesarean section--the effect of the surgical technic on postoperative febrile conditions].
The aim of the authors is to study the influence of the figure-of-eight suture of the uterine wall on the postoperative febrile complications. 1018 women, delivered with Caesarean were followed. 937 of them with conventional two layer suture of the uterine wall and the rest 81 with a figure-of-eight suture. Postoperative febrile complications were 15.58% in those with two layer suture against 3.5% in the rest 81. Using dispersion analysis the authors point that the on the type of uterine wall suture depends the rate of the postoperative febrile complications. The rate of influence of the figure-of-eight suture is up to 10%. Having in mind that this factor "suture", should be considered as 99% influential with a risk for mistake no more than 1%--F (8.06) > FT (6.64). The results presented show that the figure-of-eight suture is to be preferred to the conventional two layer suture of the uterine wall.
[The intrauterine ponderal index as a prognostic factor in fetal retardation].
The authors aim at finding the connection between the intrauterine ponderal index (IUPol) and the neonatal ponderal index (NPol) and to estimate the efficiency of IUPol in the prediction of the asymmetric growth retardation in the new born babies with NPol below 2SD for the corresponding gestational age. 142 patients were examined. The foetus weight was calculated by the formula: EFBW = 1,4 x BPD x FL - 200, and the foetus length was calculated by the formula: 6,18 x 5,9 x FL. The authors concluded that the good sensitivity and specificity of the application of IUPol in the diagnostics of the asymmetric growth retardation need wider use of this method and the IUPol can be used for the elimination of the fetal retardation, because of the high predictable level of the negative test.
[The role of routine ultrasonic screening in the antenatal diagnosis of fetal retardation].
The authors aim to evaluate the utility of ultrasound biometry in the diagnosis of IUGR. In a prospective study over 2.5 year period 142 pregnants at risk for IUGR were followed and their ultrasound results compared to those of 50 controls, investigated once after the 24 gestational week. The authors conclude that: BPD and FAC, evaluated only once, are unreliable in IUGR diagnosis; FAC is the most sensitive and specific index in onefold fetal biometry, particularly after the 34 gestational week; combing linear with non-linear parameters significantly increases.
[The dependence of fetal weight and fetal length at birth on the site of placental attachment].
The present study shows the connection between the location of the placenta in utero and the neonatal weight and length after delivery and also the relative part of abdominal delivery in relation to placental location. 289 pregnant women have been examined with ultrasonography in the III trimester of pregnancy. The results show that the neonatal length and the weight are normal when the placenta is anterior, posterior or fundal. The least neonatal weight and length have been measured in cases of placenta praevia. No correlation was found between maternal age and placental location.
[Doppler velocimetry of the fetal and the uterine-placental blood flows in pre-eclampsia and fetal retardation].
The aim of the authors is to point out the value of the Doppler velocimetry in the prediction of perinatal distress and the place of Doppler investigation in the management of high risk fetus. In 17 pre-eclamptic and 20 normotensive pregnant women, the blood flow velocity in the uterine and umbilical artery was investigated. It was proved that the changes in the blood flow velocity are feature of some placental disturbances that lead to fetal retardation. The place of that method is controversial for active obstetric management.
[Doppler velocimetry and fetal retardation--its diagnosis and management].
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[Hysterectomy in obstetrical practice (1979-1990)].
Caesarean hysterectomy and hysterectomy after vaginal delivery from 1979 to 1990, the indications, the complications and the mother's outcome are retrospective investigated. By 41010 births the hysterectomy rate is 0.068%, caesarean hysterectomy-15 (0.056%), and hysterectomy after vaginal delivery-12 (0.030%). The common est caesarean hysterectomy indications are infected uterus, haemorrhage, myoma, carcinoma colli uteri (80%). Haemorrhage and rupture uteri (75%) are the general hysterectomy indications after vaginal birth. A low complication rate is found out, 3 women are deceased (11.11%) in the group of hysterectomy after vaginal delivery. The authors have underlined benefits of the preferred recently organ keeping approach.
[A program for the antenatal diagnosis and management of fetal retardation at the Obstetrical-Gynecological Clinic of the Medical University of Pleven (preliminary report)].
The goal of this preliminary report is to define the principal stages of a program for antenatal diagnosis and management in cases of IUGR that has been introduced in practice in the Department of Obstetrics and Gynaecology at the Medical University--Pleven. We present a modified scoring system after A. Wennergren and K. Karlsson (1982) that was distributed to all primary obstetrics care phases of the city and the region for screening of all pregnancies at risk for IUGR. alpha-FP levels in the amniotic fluid and in maternal blood serum are followed according to the indication. Ultrasound follow-up of 8 biometric parameters of the foetus is performed at 2 weeks intervals. The scoring system for foetal biophysical profile after A. Vintzileos (1983) in combination with the AF indexers is introduced as a routine practice. Foetal lung maturation is surveyed by quantitative obtaining of lecithin/sphingomyelin ration in the AF after Gluck (1974). Decision on way and time of delivery is made based on the complex results.