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T Axéll

Publications and source records attributed to T Axéll.

81 records · Page 5Linked to original sources
PubMed1976

A prevalence study of oral mucosal lesions in an adult Swedish population.

The prevalence of oral mucosal lesions in Sweden is virtually unknown. Available prevalence figures concern but a few types of lesions and relate to highly selected, special populations. Investigations on general populations are sparse also in other countries. The aim of the present study was to survey the occurrence of oral mucosal lesions in a relatively large general population in Sweden. The study was performed in collaboration with a health screening organization in the middle of Sweden. The populations of two municipalities in the County of Uppsala were investigated. A mobile health screening group visited several places in the selected area and during the time of the present investigation a total of 30,118 persons, aged 15 years or above, were summoned. Of these, 62% or 18.659 individuals attended and were examined. The non-participants became the subject of a special investigation for which every fifth individual, or 2.292 persons, was randomly sampled. After a second summons, 933 persons presented for examination. Through personal contact, an additional 741 individuals were examined in private homes, places of work, hospitals, old age homes and other institutions. The final non-participation, representing 10.3% of the total population, was considered to have but a marginal influence on the results of the study. The diagnostic procedure was based on clinical criteria set forth especially for the investigation. The validity of the final diagnoses was evaluated by, for instance, inter-examiner tests and comparisons between clinical diagnoses and histologic descriptions and was found to be acceptable. Tests of the reliability were, among else, undertaken through re-examinations and indicated, that underregistration apparently occurred for a few of the lesions investigated. The prevalences of about 60 oral mucosal lesions were recorded and compared with previous findings. Notably high prevalences were found for focal epithelial hyperplasia (0.11%), leukoedema (49.07%), geographic tongue (8.45%) and lichen planus (1.85%). For some lesions prevalence figures are difficult to compare with findings from previous studies. This includes lesions which are directly or indirectly related to local etiologic factors such as denture status and tobacco habits. As regards these factors basic information has been collected and will be used for further analyses. The collected total material has also been designed to form the basis for longitudinal studies of, for example, precancerous lesions.

Adolescent↗
PubMed1976

The relation of the clinical picture to the histopathology of snuff dipper"s lesions in a Swedish population.

The relation of the clinical picture of snuff dipper's lesions to the histopathological appearance was studied in 114 male dippers aged 20-88 years. Histological study revealed increased epithelial thickness, a vacuolated surface layer with wavelike, eosinophilic spikes directed toward the surface having a narrow, eosinophilic band as a demarcation toward the prickle cell layer, acanthosis, and a slight inflammatory reaction. Thirteen cases showed an increased number of eosinophilic granulocytes, and nine cases contained amorphous, weakly eosinophilic areas in the connective tissue papillae. No epithelial dysplasia was observed. Increased epithelial thicknees, especially the presence of a vacuolated surface layer, was the only histologic feature that could be correlated with the severity of clinical appearance of the lesions. Deeply located changes, like inflammation and amorphous areas, however, were not reflected in the clinical grading of the lesions.

Adult↗
PubMed1975

A preliminary report on prevalences of oral mucosal lesions in a Swedish population.

A study has been conducted to assess the prevalence of oral soft tissue lesions. In cooperation with the public health screening organization of the County of Uppsala in Sweden, all inhabitants older than 14 years of age in two communities, Håbo and Enköping, will be called for examination. So far, 8,696 individuals have been examined. Preliminary prevalence figures on 33 lesions are reported.

Adolescent↗
PubMedDate not supplied

Xerostomia.

This communication describes the etiology, frequency, and various symptoms involved in the phenomenon of dry mouth and also discusses in detail the objective tests generally used when evaluating patients for xerostomia as the oral component of Sjögren's syndrome. It is stressed here that no single test has a sufficiently high specificity and sensitivity and consequently we recommend that at least two tests should give abnormal results before the xerostomia diagnosis is accepted.

Biopsy↗
PubMedDate not supplied

Registration procedures and exchange of data in the Sjögren's syndrome research team with special reference to the oral component.

The management of patients with Sjögren's syndrome and research on diagnostic procedures and treatment modalities is to a great extent a co-operation procedure between specialties such as rheumatology, ophthalmology and oral medicine. Efficient registration and handling of data between those disciplines is of the utmost importance for the evaluation of diagnostic criteria and therapeutic measures. Routines for the handling of pertinent data between an EDB center and different clinics are suggested in this article. For the efficient registration a package of forms is also demonstrated. This package contains one main chart and separate charts for registration of detailed information from each discipline involved.

Eye Diseases↗
PubMedDate not supplied

Sjögren's syndrome: terminology.

In spite of our continuously improved pathobiological understanding, there is still no consensus on terminology and disease criteria in Sjögren's syndrome (SS). This survey points out discrepencies in the current description of the syndrome, and argues for a new classification model. We suggest that the present nomenclatures for the global disease (Sjögren's disease) and disease subsets (primary and secondary SS) be retained until additional pathobiological insights give rise to new and descriptive terms. We do find evidence, however, to support a new terminology and classification of the main immunoinflammatory manifestations of primary SS. Accordingly, three "exocrine" and four "non-exocrine" subgroups of disease manifestations are here defined. The usefulness of the proposed model should be evaluated in clinical studies and in a debate engaging all of the medical specialities involved.

Autoimmune Diseases↗