Biomedical subjects

T Fuse

Publications and source records attributed to T Fuse.

93 records · Page 6Linked to original sources

PubMedDate not supplied

Short-term outcome and prognosis of acute low-tone sensorineural hearing loss by administration of steroid.

Acute low-tone hearing loss (ALHL) is a typical type of hearing loss in Ménière's disease and thought to be caused by endolymphatic hydrops in the inner ear. We treated 40 patients with ALHL by administration of the steroid and the early outcome and prognosis of the hearing level was retrospectively evaluated. The prognosis was generally determined within 7-10 days after administration of steroid. High-dose steroid cured some patients who failed to recover with low-dose steroid therapy. Our results showed that steroid is one of the effective therapies for ALHL and supported that etiology of ALHL involves an immune response.

Acute Disease↗

PubMedDate not supplied

Bilateral hearing loss due to viral infection.

We encountered 2 patients with bilateral hearing loss due to the mumps virus in one and the varicella-zoster virus in the other. Each virus was identified by a serological test, and virus-specific IgG and IgM antibodies were detected in the sera. In both patients, hearing loss on the contralateral side occurred a few days after that on the initially affected side, but vestibular function was normal. Although therapy included the administration of steroids, antiviral agents and hyperbaric oxygen, the bilateral hearing loss remained unchanged in these 2 patients. Both required the use of a hearing aid after discharge.

Adult↗

PubMedDate not supplied

Frequency specificity of amplitude-modulation-following response detected by phase spectral analysis.

To investigate the frequency specificity of steady-state responses elicited with a sinusoidally amplitude-modulated tone (amplitude-modulation-following response, AMFR), AMFR at different carrier frequencies were examined in 15 subjects with normal hearing, 12 patients with abrupt high-frequency hearing loss, 5 patients with low-frequency hearing loss and 1 patient with mid-frequency hearing loss. The stimulus was a sinusoidally amplitude-modulated tone with a modulation frequency of 40 Hz and modulation depth of 95%. Carrier frequencies were from 250 to 4000 Hz in normal subjects and from 250 to 8,000 Hz in hearing-impaired subjects. Fridman's phase spectral analysis was conducted for automatic detection of response. The thresholds of AMFR were distributed within 30 dB nHL at all carrier frequencies in normal subjects. In the hearing-impaired subjects, AMFR thresholds were between 0 and 25 dB above the behavioral threshold at all carrier frequencies. The threshold patterns of AMFR detected by phase spectral analysis very closely resembled the corresponding audiogram patterns in all types of hearing impairment. AMFR is thus shown to have a very good frequency specificity.

Acoustic Stimulation↗