PubMed Health⌕ Search

Biomedical subjects

T GUTHE

Publications and source records attributed to T GUTHE.

At least 37 records · Page 2Linked to original sources

Some important aspects of yaws eradication.

The purposes of a yaws mass campaign are to eradicate yaws and to improve the environmental sanitation and standard of living of the people so that its re-introduction will be impossible. In a mass treatment campaign the importance of latent cases and contacts in maintaining the disease must be taken into account. The treatment of this group of the population, in addition to all active cases, hastens the success of the campaign.Resurveys at regular intervals must be carried out until the prevalence of active yaws is low and there are adequate facilities to continue the consolidation phase of the campaign. All the population should be seen at each survey. Serological screening is used to guide public health activities.All campaigns and post-campaign activities should be planned and budgeted for before the activities start. Campaigns should expand as compact areas and should be co-ordinated with similar campaigns in adjacent countries. Adequate supervision of field staff, the intelligent co-operation of the people and their leaders and continuous project evaluation are essential for the eradication of yaws.

Biomedical Research↗

A decade of reorientation in the treatment of venereal syphilis.

As experience with penicillin in the treatment of venereal syphilis has grown over the last decade, this drug, used without adjuvants, has become increasingly widely accepted as being effective, convenient, non-toxic, and relatively inexpensive. Metal chemotherapy required the use of repeated subcurative doses over a long period of time and was essentially suppressive in character; penicillin can be given in the form of repository preparations which ensure a treponemacidal blood-level of long duration. These can be given in large single doses or in repeated smaller doses; the therapeutic results will not vary whichever of these procedures is used.In the first part of this paper, the authors discuss the effect of penicillin and the time factor, the choice of penicillin preparation, the mode of administration, and the reaction to infection with Treponema pallidum. In the second part, they consider the present status of penicillin therapy in venereal syphilis, dealing with the principles of follow-up and control; with the treatment of early, latent, late, and congenital syphilis; and with the treatment of incubating syphilis and contacts.

Humans↗