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T Greiner

Publications and source records attributed to T Greiner.

At least 37 records · Page 2Linked to original sources
PubMed2000

Five-year follow-up of a food-based vitamin A intervention in Tanzania.

OBJECTIVE: : To evaluate the long-term effects of a horticultural and nutrition education intervention in rural Tanzania. DESIGN: : A quasi-experimental post-test design was used. SETTING: : The research was carried out in 10 villages in Singida region, Tanzania. SUBJECTS: : Mothers and their children aged 6-71 months (n = 236) from an experimental (Ilongero) and control (Ihanja) area were interviewed regarding knowledge and practices related to vitamin A nutrition. Intake of vitamin A-rich foods by the children during the 7 days prior to the interview was recorded. Stools were examined for helminths and serum samples were analysed for retinol and C-reactive protein (CRP) (n = 146) for the children aged 12-71 months. RESULTS: : Knowledge and practices were more favourable to vitamin A intake in the experimental area than in the control area, and an increased frequency of intake of green leaves was associated with higher serum retinol values. The experimental area had lower mean serum retinol levels (13.7 microg dl(-1), n = 75) than the control area (19.3 microg dl(-1), n = 71). One likely confounder was the higher helminth infestation in the experimental area (n = 75, 79%) than in the control area (n = 71, 49%) (P < 0.001). Children with helminths (n = 94) had a lower mean serum retinol level than those without (n = 52) (12.3 +/- 5 vs. 24 +/- 10 microg dl(-1); P = 0.001). CONCLUSIONS: : Food-based vitamin A programmes can make sustainable improvements in knowledge and dietary practices but these may not necessarily be reflected in increases in serum retinol. Programme implementation and evaluation should take confounders into consideration as, in this case, helminth infestation.

Agriculture↗
PubMed2000

How exclusive is exclusive breastfeeding? A comparison of data since birth with current status data.

BACKGROUND: There is no accepted and widely used indicator for exclusive breastfeeding since birth. Indeed, the difference between 'current status' data on exclusive breastfeeding and data on 'exclusive breastfeeding since birth' is rarely recognized. We used data from a longitudinal study to examine this issue. METHODS: A descriptive longitudinal, prospective study design was used in which 506 mother-infant pairs were included. The mothers completed daily recordings on infant feeding during the first nine months after birth. A research assistant conducted fortnightly home visits with structured interviews. The resulting data on breastfeeding patterns are presented in two different ways: analysis of 'current status' data based on a single 24-hour recording of infant feeding at 2, 4 and 6 months of age, and analysis of data 'since birth', i.e. data on infant feeding for every day, starting from birth until the ages of 2, 4 and 6 months. RESULTS: A wide discrepancy between the results obtained from the two analyses was found. The difference in the exclusive breastfeeding rate was over 40 percentage points at both 2 and 4 months of age (92% versus 51% at 2 months and 73% versus 30% at 4 months) and 9 percentage points at 6 months (11% versus 1.8%). CONCLUSIONS: Current status indicators based on a 24-hour period may be inadequate and even misleading for many purposes. We propose that in many studies an indicator called 'exclusive breastfeeding since birth' could be added.

Adult↗
PubMed1999

Coverage and cost of iodized oil capsule distribution in Tanzania.

Distribution of oral iodized oil capsules (IOC) is an important intervention in areas with iodine deficiency disorders (IDD) and low coverage of iodized salt. The mean reported coverage of 57 IOC distribution campaigns from 1986-1994 of people aged 1-45 years in 27 districts of Tanzania was 64% (range 20-96%). This declined over subsequent distribution rounds. However, due to delayed repeat distribution, only 43% of person-time was covered, based on the programme objective of giving two IOC (total 400 mg iodine) at 2-year intervals. Three different capsule distribution strategies used in 20 distribution rounds in 1992-1993 were analyzed in depth. Withdrawal of financial support for district distribution expenses under the 'district team' strategy, and the subsequent change to integrated 'primary health care' distribution, increased delays and capsule wastage. The third, more vertical strategy, 'national and district teams', accomplished rapid distribution of IOC about to expire and subsequently a return to the initial 'district team' allowance strategy was made. Annual cost of 'district team' distribution was 26 cents per person (400 mg iodine/2 years). Cost analysis revealed that the IOC itself accounts for more than 90% of total costs at the levels of coverage achieved. IOC will be important in the elimination of IDD in target areas of severe iodine deficiency and insufficient use of iodized salt, provided that high coverage can be achieved. Campaign distribution of medication with high item cost and long distribution intervals may be more cost-effectively performed if separated from regular PHC services at their present resource level. However, motivating health workers and community leaders to do adequate social mobilization remains crucial even if logistics are vertically organized. Insufficient support of distribution expenses and health education may lead to overall wastage of resources.

Adolescent↗
PubMed1999

Evaluation of the effect of a breastfeeding message integrated into a larger communication project.

Most breastfeeding project evaluations examine the effects of separate projects and many do not use experimental designs. We evaluated the impact during the 3rd year (March 1992-March 1993) of a simple breastfeeding message integrated into a large-scale 3 year vitamin A project in northern Bangladesh. It encouraged mothers to breastfeed for at least 2 years. Less formally, mothers were also advised to give colostrum. In both project (experimental) and non-project (control) areas, the proportion of mothers of children aged 1-6 years who said they gave colostrum increased from about 69 per cent to about 77 per cent. However, children born during the year that transpired between the pre- and post-surveys were too young to be included in the post-survey. Thus this difference is an example of women reporting what they perceived as the norm or the 'correct' answer instead of what they actually did with their children. Thus the norm changed during the evaluation year, but it did so equally in both project and non-project areas. Although reported breastfeeding levels remained stable among older groups, the proportion of children in the 2nd and 3rd years of life reported to be currently breastfeeding increased to a similar extent in both areas. This could indicate either a change in perception or a change in behaviour. Suckling frequency, not mentioned in local or national breastfeeding promotion, was unchanged in both areas at about 15 times a day for children in the 2nd year of life, and maintained at about eight to 10 times a day even for the small proportion who were still breastfed in the 5th (about 9 per cent) or 6th (about 2 per cent) years of life. While project messages (especially by radio) could have spread to the nearby non-project area, it is unlikely that the impact would be equal. More likely these changes were the result of secular changes occurring at this time throughout Bangladesh. Thus this evaluation found no evidence that the integration of a simple message about breastfeeding into a larger project had any measurable effect in the project area compared to the non-project area. More effective approaches may be required, tailored to the particular needs of women in the area.

Adult↗
PubMed1999

Determinants of the breastfeeding pattern among working women in São Paulo.

The needs of breastfeeding women who work away from home differ from those of other women, particularly those who breastfeed exclusively. Sixty-nine factory workers were interviewed in São Paulo, both during pregnancy and when they returned to work. Median durations of exclusive (EBF), predominant (PBF), and any breastfeeding (BF) were found to be 10 days, 70 days, and 150 days, respectively. Despite having used the 4-month leave to which they were entitled, by 1 month, 86% of the respondents had given tea, 50% water, and 42% artificial baby milk. Only 2 women were still exclusively breastfeeding when they returned to work. Various personal characteristics were associated with longer duration of breastfeeding. Maternity ward routines were generally not supportive, but duration of PBF was longer where better support was received. Duration of EBF was longer among women with support for breastfeeding at work, and shorter for those working on weekends or doing shift work. Thus, women may have adjusted their feeding patterns based on whether or not they anticipated workplace support. Only weekend work and socioeconomic status were linked to shorter duration of breastfeeding. Stronger social and health care support for EBF may be needed before the full impact of workplace support can be usefully studied in Brazil.

Adult↗
PubMed1997

[Possibilities and limitations of breast-feeding among formally employed women].

INTRODUCTION: Studies carried out on breastfeeding and working women are difficult to compare. Breastfeeding practices among formally employed women in Brazil have not been much studied, despite important changes in public policies such as the extension of maternity leave to 120 days. OBJECTIVES: A description of breastfeeding patterns among women employed in factories and the constraints and opportunities involved in conciliating breastfeeding and work. MATERIAL AND METHOD: An exploratory study was carried out in 13 factories in S. Paulo city in 1994, where all women in the 3rd trimester of pregnancy were interviewed (76), and re-interviewed (69) when they went back to work (around 5,4 months after delivery). RESULTS: Breastfeeding initiation was found in 97% of women and the median duration was 150 days. The exclusive breastfeeding and predominant breastfeeding rates were, respectively, 10 and 70 days of median duration. Higher socio-economic status and nursery facilities and the existence of a place in which to extract and store the mother's milk at the workplace were factors associated with longer duration of breastfeeding. Other factors such as flex-time and work out of the production-line also showed a significant relation to longer duration of breastfeeding in the factories studied. CONCLUSION: Maternity leave is widely taken advantage of and highly beneficial for the majority of working women as regards breastfeeding, but other factors are important in maintaining lactation, such as circumstances which permit closer mother-child contact and/or the extraction of human milk during the working day.

Adult↗
PubMed1996

The concept of weaning: definitions and their implications.

"Weaning" is usually said to refer to the entire process during which the infant changes from full dependence on breast milk to complete independence from it. However, "wean" is sometimes used to refer to provision of an "educational diet" during the first six months when exclusive breastfeeding is the ideal; to complementary feeding; to replacement of breastmilk; or to the cessation of breastfeeding. The processes involved are illustrated by a graph that theoretically compares the infant's nutritional needs with the proportion of those needs that can come from breastmilk under ideal circumstances. The development of consistent, relevant research, policies and programs on young child feeding may be particularly hindered by the failure to discriminate between complementation and replacement.

Age Factors↗
PubMed1995

Neurogenic flare responses are heterogeneous in superficial and deep layers of human skin.

Infrared thermography and video image analysis were used to compare the development of the neurogenic flare response in deep and superficial skin layers. Neurogenic vasodilatation was induced by injection or iontophoretic application of histamine. Thermograms were recorded every 10 s to evaluate the local warming reaction. Color-video image analysis was used for computerized delineation of the visible flare. Images derived from video analysis were superimposed to the thermograms after linear transformation. The thermal reaction started within 10 s simultaneously at 2-5 distinct spots after histamine application at distances of 4-25 mm from the application site while the flare reaction seemed to spread from the application site when it became visible after a delay often exceeding 20 s. The visible flare but not the warming reaction was suppressed by topically applied local anesthetic (EMLA). Warming at focal spots was also observed during post-occlusive hyperemia. About 70% of these spots were identical to those activated by histamine. The results indicate that the vascular axon reflex is differently organized in different layers of the skin.

Adult↗
PubMed1995

Ploidy analysis by flow cytometry and fluorescence in situ hybridization in hydropic placentas and gestational trophoblastic disease.

Placentas with hydropic change may be hydropic degeneration (HD) or gestational trophoblastic disease (GTD), partial (PM) or complete (CM) hydatidiform mole. The separation of HD from PM and PM from CM by histological findings may be problematic in some cases and can be clarified with ploidy analysis. Fluorescence in situ hybridization (FISH) using a probe to chromosome 7 (D7Z1) was applied to tissue cut from paraffin blocks from 10 histologically representative cases each of HD, PM, and CM on which ploidy had been previously confirmed by flow cytometry from paraffin embedded tissue. Villous stromal cells and nonproliferative trophoblast were examined for number of signals/cell and percentage of cells/placenta with three hybridization signals. The mean number of hybridization signals/cell was HD 1.14; PM 1.79; and CM 1.17, with statistical significance between HD and PM (P < .0001), and PM and CM (P < .0001). The mean percentage of cells/placenta with three hybridization signals was HD 1.10%, PM 23.1%, and CM 2.11%, with statistical significance between HD and PM (P < .0001), and PM and CM (P < .0001). In addition, there was no overlap in the mean percentage of cells with three hybridization signals between HD and PM, and PM and CM. Chromosome 2 probe (D2Z1) was applied to tissues that had three chromosome 7 signals to exclude trisomy, and in all cases three signals were present confirming triploidy in PM. FISH can identify diploid and triploid hydropic placentas in paraffin-embedded tissue to assist in differentiating HD from PM, and PM from CM.

Chromosomes, Human, Pair 2↗
PubMed1994

Flow cytometric detection of neoplastic T cells in patients with mycosis fungoides based on levels of T-cell receptor expression.

The authors report the flow cytometric detection of neoplastic T cells in the peripheral blood of four out of five (80%) patients with peripheral blood involvement with mycosis fungoides (Sezary syndrome) based on the levels of T-cell receptor expression as measured by CD3 and TCR-alpha beta staining. Antigen receptor expression was abnormal in terms of increased density of surface CD3 or TCR-alpha beta per cell. Other immunophenotypic abnormalities were present in three of these patients. However, in one patient abnormal T-cell receptor expression was the only immunophenotypic evidence of neoplasia, although morphologically abnormal lymphocytes were present and a T-cell clone was detected by polymerase chain reaction (PCR). In another patient, the authors were able to detect development of a new, more aggressive neoplastic T-cell population based on levels of T-cell receptor expression. Levels of T-cell receptor expression may be of diagnostic utility in the evaluation of peripheral blood for the presence of neoplastic T-cell populations.

Aged↗