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Biomedical subjects

T H Edna

Publications and source records attributed to T H Edna.

At least 37 records · Page 2Linked to original sources

Blood transfusion and survival following surgery for renal carcinoma.

The effect of peri-operative blood transfusion on survival after surgery for renal carcinoma was studied in 201 patients. In addition to blood transfusion, several other factors were included in a multivariate analysis. Using Cox's proportional hazards model, transfusion of more than 4 units of blood was found to be an independent prognostic factor in addition to tumour stage, erythrocyte sedimentation rate and macrohaematuria.

Adult↗

Long-term results after 'floppy' Nissen/Rossetti fundoplication for gastroesophageal reflux disease.

Eighty-two patients (median age, 51 years; range, 27-87 years) with refractory gastroesophageal reflux disease (GERD) underwent floppy Nissen/Rossetti fundoplication during the period 1980 to 1990. The median postoperative hospital stay was 5 days (3-16). Median follow-up was 72 months and included endoscopy and a clinical and a questionnaire assessment. Subjective symptoms of reflux were abolished in 98%, and 96% of the patients were satisfied with the results. Endoscopy showed healing of the esophagitis in 98%. There had been no disruption of the fundoplication. Twenty patients complained of gaseous distention and increased flatulence; only two of them had severe problems. Three patients were unable to belch. In conclusion, the floppy fundoplication has been an effective operation with no deaths, a low incidence of morbidity and adverse side effects, and without a tendency for late failure.

Adult↗

[Diagnosis and routines in abdominal injuries].

In patients with suspected intra-abdominal injuries the diagnostic process must conclude with a decision to do a laparotomy or to observe the patient. If the circulation is unstable because of intra-abdominal bleeding, or the patient has peritonitis, he must be operated on without delay. Otherwise, a range of different diagnostic tools may be chosen. It is wise to work according to a plan and to choose diagnostic methods that are able to give considerable help in deciding whether to operate or not. Ultrasonography or computed tomography will often be good choices.

Abdominal Injuries↗

[Abdominal injuries. Occurrence and outcome].

A retrospective study of intra-abdominal injuries treated during the ten-year period 1977 to 1986, show that road traffic accidents were responsible for the injury in 38% of 221 patients. Accidents from sports and recreation were the cause in 23% of the cases. The median age was 19 years. Renal injuries were most common, followed by splenic injuries. 119 patients (54%) were operated for abdominal injury. 90 patients (41%) needed blood transfusions and 29 (13%) were treated by respirator. 95 patients had concommitant extraabdominal injuries. The overall lethality was 9%.

Abdominal Injuries↗

[Grading and prognosis of abdominal injuries].

The present study was carried out in order to find out the relationship between injury grading and the use of different resources and the result of the treatment in patients with intra-abdominal injuries. The injuries were graded according to two trauma scores: The Injury Severity Score and the Norwegian Injury Score. In 221 patients with intra-abdominal injuries there were good correlations between these two scores and the time of hospitalization, units of blood transfusions, need for respirator treatment and lethality.

Abdominal Injuries↗

Return to work and social adjustment after traumatic head injury.

During follow-up of 485 adult patients with mainly mild head injury 27% of the patients were unemployed after an observation period of 3-5 years (mean 4.0 years). The length of sick leave during the last 3 years was longer than for a control group. Reduced physical capacity and time of sick leave during the last 3 years were the variables which were most closely associated with unemployment at follow-up. The long term family life, contact with friends and income were less favourable in the head injured patients than in the control group.

Absenteeism↗

Late post-concussional symptoms in traumatic head injury. An analysis of frequency and risk factors.

During follow-up of 485 adult patients with traumatic head injury, 51% of the patients reported new post-concussional symptoms after an observation period of 3-5 years (mean 4.0 years). Most data, including the level of consciousness on admission, length of post-traumatic amnesia and days of hospitalization were poor parameters for predicting which patients would suffer late complications. A few variables were statistically of predictive importance: Sex, repeated head injury and skull fracture. Age was a risk factor for multiple complaints.

Adolescent↗

Indomethacin in the treatment of ureteral colic: is fluid restriction necessary?

The effect of fluid load on pain was estimated in 60 patients with acute ureteral colic treated with 50 mg. intravenous indomethacin. One group received 3 l. fluid intravenously, while in another group all fluids were withheld for 6 hours. Pain was assessed with a visual analogue scale. No intergroup difference in regard to pain was found after 1, 3 and 6 hours of observation.

Adolescent↗

Head injury in road traffic accidents. A prospective Study in Trøndelag, Norway, 1979-80.

The purpose of the present prospective investigation was to study the epidemiology of head injuries sustained in road traffic accidents. The characteristics of all 503 head-injured patients admitted to hospitals in the two counties of Trøndelag province, Norway, in 1979 and 1980 are described. The annual incidence was 89 per 100 000 inhabitants. There was a male preponderance in all categories of victims. The highest male to female ratio was found in motorcyclists and mopedists (6.3:1). Pedal cycle accidents accounted for 33% of all accidents, constituting the most common cause of head injury on the roads in the period from May to the end of September. There were more pedal cycle accidents in the present series than in previous studies on road traffic accidents.

Accidents, Traffic↗

Hospital admitted head injury. A prospective study in Trøndelag, Norway, 1979-80.

Head injury ranks among the leading causes of disability and death in the prime of life. The purpose of the present prospective investigation was to study head injuries necessitating hospital admission in our region. The characteristics of 1124 such head injuries in Trøndelag in 1979-80 are presented. The annual incidence was 200 per 100 000 inhabitants. Young males were most often affected. The incidence was higher in males than in females in all age ranges. Road traffic accidents were the most common cause of head injury, but home accidents had higher rates of skull fractures and intracranial haematomas. Both lethality and duration of hospitalization increased with age.

Accidents↗

Risk factors in traumatic head injury.

The purpose of the present prospective study was to compare different risk factors in head injuries with one known risk factor, the level of consciousness at admission. The series includes 1,120 head-injured patients admitted to hospitals in Trøndelag, Norway, in 1979 and 1980. In addition to the level of consciousness at admission, the following factors seemed to be important for the outcome: age, pupillary light reactions, intracranial haematomata, associated extracranial injuries and skull fracture.

Adolescent↗

Acute ureteral colic and fluid intake.

In the treatment of acute ureteral colic opinions differ regarding the consequences of fluid intake. This study was undertaken to evaluate a possible relationship between fluid load and the pain. One group of patients received 3 liters of fluid intravenously, while in another group all fluids were withheld. No intergroup differences as regards pain was found after 6 hours of observation.

Acute Disease↗

Acute traumatic intracranial haematoma and skull fracture.

The value of plain skull radiographs in acute head injury has been much debated. A prospective study is presented of the isolated predictive value of skull fracture, in addition to the level of consciousness on admission after trauma, for acute intracranial haematoma. In head injuries which were followed by such haematoma, skull fracture was significantly more common than in injuries without this sequel. The association was found at all levels of consciousness and was most pronounced in patients with minor or no diminution of consciousness on admission. Fractures crossing a vascular groove had additional predictive significance.

Adolescent↗