Alcohol influence and head injury.
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Biomedical subjects
Publications and source records attributed to T H Edna.
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A study of 10 patients treated non-operatively for Achilles tendon ruptures is reported. Re-ruptures occurred in three patients. The end-results as regards plantar flexion power and ankle mobility were comparable with those obtained in 24 patients treated operatively.
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OBJECTIVE: To examine the association between blood transfusion and infective complications after biliary operations. DESIGN: Retrospective cohort study. SETTING: District hospital. SUBJECTS: 875 consecutive patients who required biliary operations. MAIN OUTCOME MEASURES: Postoperative infective morbidity in hospital. RESULTS: 73 patients (8%) developed postoperative infections in hospital. Univariate analysis showed that the development of infections was significantly associated with blood transfusion (p < 0.001), stones in the common bile duct (p < 0.001), operations on the common bile duct (p < 0.001), T-tube drainage (p < 0.001), duration of operation (p = 0.008), and age (p = 0.03). Multivariate logistic regression analysis showed that only blood transfusion and stones in the common bile duct were independent predictors of infection. The corrected odds ratios for infection were 4.7 (95% confidence interval (CI) 2.4 to 9.3) when 1-3 units of blood were given and 5.6 (95% CI 2.3 to 13.6) when more than three units were given. CONCLUSION: Transfusion is an independent risk factor in the development of postoperative infection in hospital in patients who have had biliary operations.
BACKGROUND/AIMS: The aim of the study was to compare the short- and long-term outcome of older and younger patients treated for colorectal cancer. We also wanted to study whether age was independently associated with post-operative mortality. METHODOLOGY: We conducted a retrospective study of 503 consecutive patients treated for colorectal cancer. One hundred and six (21%) were 80 years of age or older. The median follow-up was 5.5 years (2-16.8 years) or until death. RESULTS: Post-operative mortality was 6% (0.7% in patients less than 65 years and 16% in patients over 80 years). Multiple logistic regression analysis showed that age, emergency operation, advanced T-stage, and ASA-class were each independently related to post-operative mortality. The overall estimated 5-year survival rate was 59% in patients less than 65 years and 24% in patients over 80 years. The cancer specific 5-year survival was 62% in patients less than 65 years and 45% in patients over 80 years. CONCLUSIONS: The study demonstrated that age was an independent risk factor for post-operative mortality. In very old patients surviving the post-operative period, the long-term outcome was good. Advanced age alone should not be used as a criterion to deny surgery for colorectal cancer.