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Biomedical subjects

T I Ivanova

Publications and source records attributed to T I Ivanova.

At least 19 recordsLinked to original sources

[Oxidative phosphorylation in liver mitochondria in toxic form of experimental form of influenza].

The effect of free radical processes on the oxidation-phosphorylation activity in the liver of CBA-mice has been studied, using a model of toxic form viral infection. The EPR-spectroscopic and electrochemical methods applied in the study of animals infected with pathogenic form of the influenza virus made it possible to reveal a decrease in the activity of the respiratory chain in mitochondria. This seems likely to be due to accumulation of endogenic nitric oxide in the liver tissue.

Animals

[Generalized mastocytosis--hemoblastosis of mast cells].

A review of literature has been presented including current data on bone marrow genesis functional role of mast cells in the human body, as well as characteristics of the main clinical variants of mastocyte tumor proliferations (solitary mastocytoma, urticaria pigmentosa, generalized mastocytosis). Clinicomorphological picture and positive results of the treatment with the Soviet cytostatic spirobromine of two patients suffering from generalized mastocytosis are described.

Aged

[Effect of cadmium ions on the respiration, cation transport and morphology of the liver mitochondria in the rat and the lamprey].

The influence of Cd2+ on the function and structure of liver mitochondria of rats and lamprey (Lampetra fluviatilis L.) has been studied in vitro. It is shown that Cd2+ can penetrate into the mitochondrial matrix due to Ca2+-transport mechanism. Being stored in the mitochondria, Cd2+ inhibits respiration and an energy dependent transport of penetrating cations (Cs+-valinomycin), and disturbs passive permeability of the inner mitochondrial membrane for monovalent cations and H+. The effect of Cd2+ on the lamprey liver mitochondria is more pronounced than in the case of rats.

Animals

[Assessment of the regulatory resources of the pial and intracerebral arteries by using mathematical modeling].

A mathematical model for estimation of regulatory abilities of pial and intracerebral arteries was used for studying the pressure - radius relationships for arteries of various calibres in passive and active states. In passive state the arteries were found to be characterized by high elasticity and low tensile force. The radius of the artery depends mainly on the smooth muscle contractile force. The data obtained suggest that the wall structure of small pial and intracerebral arteries well correspond to their function: the control of the adequate and rapid cerebral blood flow.

Biophysical Phenomena