PubMed Health⌕ Search

Biomedical subjects

T I Ivanova

Publications and source records attributed to T I Ivanova.

At least 37 records · Page 2Linked to original sources

[Effect of thallium on enzyme activity and unidirectional sodium transport in frog skin].

The cytophotometric analysis of enzyme activity in the frog skin epithelium has shown that Tl+ accumulated by cells at millimolar concentrations causes a 70-80% inhibition of both succinate and alpha-ketoglutarate dehydrogenases, while the activity of Na, K-ATPase decreased only slightly. The opposite situation was true for the ouabain treatment. The accumulation of Tl+ by frog skin caused a substantial swelling of mitochondria. It is suggested that the earlier observed inhibition of the unidirectional Na+ transport by Tl+ might be resulted from a blocking of oxidative metabolism. The same cells poisoned by Tl+ were able to maintain their ion composition presumably at the expense of glycolysis.

Animals↗

[Assessment of the regulatory resources of the pial and intracerebral arteries by using mathematical modeling].

A mathematical model for estimation of regulatory abilities of pial and intracerebral arteries was used for studying the pressure - radius relationships for arteries of various calibres in passive and active states. In passive state the arteries were found to be characterized by high elasticity and low tensile force. The radius of the artery depends mainly on the smooth muscle contractile force. The data obtained suggest that the wall structure of small pial and intracerebral arteries well correspond to their function: the control of the adequate and rapid cerebral blood flow.

Biophysical Phenomena↗