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Biomedical subjects

T Kumoi

Publications and source records attributed to T Kumoi.

At least 37 records · Page 2Linked to original sources
PubMed1991

Subglottic plasma cell granuloma: report of a case.

A case of subglottic and tracheal plasma cell granuloma masquerading as tumor invasion by thyroid malignancy was successfully treated using CO2 laser. A 55-year-old woman with a history of inspiratory stridor of almost 10 months duration was admitted to our clinic, and examinations revealed a mass in the subglottic space and trachea obstructing the airway. CT scan findings was suggestive of tumor invasion from a thyroid gland malignancy, however, histopathological examination of a biopsy specimen showed it to be plasma cell granuloma. Cases of plasma cell granuloma of the larynx and trachea are reviewed and discussed.

Female↗
PubMed1991

External septorhinoplasty in the cleft lip nose.

When the entire septum as well as the cartilaginous vault are exposed to direct vision by degloving the nasal covering, the complete extent of the deformities in cleft lip nose can be clarified. The septal cartilage is hollowed out leaving an L-shaped anterosuperior portion, whereas the intranasal structures are simultaneously altered to ensure the patency of the nasal airway. An adequate-sized piece is cut from the removed cartilage and is fitted to the anterior part of the remaining cartilage to enforce the columella, which acts as a strut to keep both lower lateral cartilages symmetrical and to create a nasal tip. Thus, a new cartilaginous pyramid with symmetrical nostrils is reconstructed. If the anterosuperior portion of the cartilage is deviated, the concave surface is scored to allow it to be straightened before the strut is fitted. Satisfactory cosmetic and functional results were obtained in most patients with adult cleft lip nose, including those associated with deviation, without any major complications.

Adolescent↗
PubMed1991

Test for otolith organs with barbecue rotation.

In the sitting position, vertical axis head rotation stimulates only the horizontal canal. In the supine position, horizontal axis rotation, so-called barbecue rotation, is a stimulus to both the horizontal canal and otolith organs. We compared dynamic otolith response to these two types of harmonic rotations in 15 normal subjects. The subjects' heads were rotated, passively with eyes open but covered, at the following frequencies: 0.17, 0.33, 0.50, 0.67 and 1.00 Hz. Head movement and eye movement were recorded by scleral search coil technique. Compensatory eye movements were present on each record. Vestibulo-ocular reflex (VOR) gain was calculated using peak-to-peak velocity of the eye and head. At all frequencies the VOR gain of horizontal axis rotation was larger than that of vertical axis rotation. This difference was maximal at the lowest frequency, 0.17 Hz, suggesting that dynamic otolith stimulus improves VOR at low frequencies.

Adult↗
PubMed1990

[The effect of IL-2 injection around the metastatic cervical lymphnode].

Six patients with squamous cell carcinoma of head and neck were treated with injection of interleukin-2 (IL-2) around the metastatic cervical lymphnodes. Lymphokine activated killer (LAK) activity in peripheral blood in administration of IL-2 showed a significant high of 13.2% at effector/target (E/T) ratio 13 compared with non-administration of IL-2 showed 4.3%. LAK activity in cervical non-metastatic lymphnodes in 6 cases of administration of IL-2 showed a significant high of 23.0% at E/T ratio 50 compared with 3 cases of non-administration of IL-2 which showed 3.7%. In the 2 evaluable courses given in patients a partial response was obtained in one case.

Aged↗
PubMed1990

[A solitary extramedullary plasmacytoma of the nasopharynx].

A 72-year-old male, complaining of epistaxis, was referred to our hospital where a physical exam revealed a tumorous mass in the nasopharynx. A subsequent immunohistopathological investigation found that the tumor mass was a plasmacytoma with IgG and a lambda chain. Electrophoresis of a serum sample revealed a normal value and there was no signs indicating a multiple myeloma on x-ray surveys of the skeleton, or from bone marrow aspiration or scintigraphy. Thus the diagnosis was an extramedullary plasmacytoma and the patient received a combined treatment of chemotherapy, radiotherapy, and surgery. Since surgery, the patient has had neither a recurrence or a metastasis of the tumor for four years and three months.

Aged↗
PubMed1990

Hyogo ear bank experience with allograft tympanoplasty--review of tympanoplasties on 68 ears.

Allograft tympanoplasties on 68 ears done between October, 1980 and December, 1986 were analyzed from the viewpoint of graft take rate and hearing improvement, and also the results were compared between draining and nondraining ears as well as among three stabilizing methods of the transplanted tympanic membrane (Type I: allograft tympanic membrane (ATM) covered with reflected epithelium; Type II: entirely covered ATM with fascia; and Type III: ATM reinforced with thin crescent fascia) and four groups of allograft materials (Group I: ATM with attached malleus and incus en bloc; Group II: ATM with attached malleus; Group III: ATM attached malleus and incus columella; and Group IV: two stage surgery with Group III material). Among the three types of stabilization in draining ears, the anatomic success rate of the tympanic membrane transplant was 27% in Type I, 56% in Type II and 90% in Type III, while in nondraining ears it was 81%, 88%, and 100%, respectively. The success rate for hearing improvement in draining ears was 40% in Group A, 44% in Group B, 33% in Group C, and in nondraining ears, it was 82%, 100%, and 82%, respectively. Our results show that allograft tympanoplasty can be successful for a well-controlled middle ear with good utility of the areolar fascia in stabilization.

Graft Survival↗
PubMed1989

Intractable retroauricular abscess associated with microtia and aural atresia--some views in relation to the congenital cholesteatoma and microtia.

Five microtic and aural atretic ears associated with intractable retroauricular abscess unresponsive to conservative treatment are reported. The pathogenesis of this abscess is primary cholesteatoma called "cholesteatoma auris congenita of atretic ear," and these lesions can be clearly explained by the embryological development of the external auditory meatus. Microtic ears with such lesions invariably have part of the cartilaginous canal patent but have an atrophic bony canal. Therefore, grade 3 microtia has never been affected theoretically. We also discuss the relationship between the retroauricular abscess and the development of the tympanic bone. The evaluation of this lesion with computed tomography is mandatory for the detection of an occult congenital cholesteatoma behind the atretic canal, and regular follow-up of the patients with microtia and aural atresia is necessary for plastic surgeons.

Abscess↗
PubMed1989

Results of tympanoplasty for congenital aural atresia and stenosis, with special reference to fascia and homograft as the graft material of the tympanic membrane.

The surgical management of congenital aural atresia is a challenging, complex procedure, and the risks are great. The otologic surgeon is responsible for keeping a patent external auditory canal and for achieving satisfactory hearing. The present report studied hearing changes that occurred after tympanoplasty and the long-term results of tympanoplasty in 12 cases of congenital aural atresia or stenosis. Patients were followed for more than 2 years after surgery. In four ears, an allograft of the tympanic membrane with an attached malleus was used, with a good graft take and hearing results. An autograft of temporal fascia was used in eight ears. Hearing acuity decreased in six of the eight ears and was maintained in two ears. Three primary surgery patients required revision surgery for postoperative restenosis of the external auditory canal. Some comments have been made with regard to this problem. Emphasis is also placed on the selection of patients for surgery using a thorough audiologic and roentgenologic evaluation.

Adolescent↗
PubMed1989

[A proposal for endonasal middle meatal antrostomy].

With increase of cases with mild chronic sinusitis, especially the cases combined with nasal allergy, endonasal sinus surgery has been substituted for Caldwell-Luc or some other modified sinus surgery in recent years. The classical inferior meatal antrostomy for maxillary sinusitis is one of the treatments of choice, though this opening is easily closed and is somewhat different from normal sinus physiology. In the middle meatal antrostomy, the opening was made via the inferior turbinate or the middle meatal wall perforated with nasal forceps. Reported here is a new technique for middle meatal antrostomy which can be easily and safely performed. At the beginning, mucosal incision is made from the agger nasi to the anterior of the inferior turbinate, dividing the mucous membrane inferomedially. Then the mucous membrane of the inferior turbinate is cut along the upper margin of it and reflected downwards. With this procedure, the frontal process of the maxilla, lacrimal bone and inferior turbinate are well exposed and well oriented in the surgical field. The pars membranacea is then cut from anterior to inferior, and removed with the uncinate process, thus entering the maxillary antrum. The antrostomy opening is made at least 1 by 1.5 cm wide. Then, the intranasal ethmoidectomy is usually done and the reflected mucous membrane of the inferior turbinate returned to its normal position. This surgery was applied to 34 patients (7 children, 27 adults), (2 antrochoanal polyps, 5 optic neuritis, 3 maxillary sinusitis, 17 pansinusitis, and 7 pansinusitis associated with nasal allergy). We have not experienced surgical complications and none of them also had closure of the antrostomy opening.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗
PubMed1988

Vulnerable site of the facial nerve. From histopathology of seven temporal bones.

In the present work, a series of studies was made of seven temporal bones taken from 5 newborns within 6 h of death. In the 5 cases considered in this study, all of which had suffered from severe circulatory disease of congenital or unknown origin, destruction of the facial nerve as well as severe congestions were noted. The following findings were common to all seven temporal bones. (1) Bleeding together with destruction of the nerve had originated in the mid-section of the tympanic portion and increased distally up to the distal portion of the mastoid. (2) Bleeding was restricted mainly to the inner side of the perineurium or in the nerve trunk. (3) There was little bleeding in the epineurium, with the exception of both temporal bones in one of the cases. Although destruction of nerve fibres and the perineurium was prominent in all cases, in six of the temporal bones, traces of nerve trunk remained as a mould, with or without erythrocytes. In one temporal bone in case 5, which survived only 16 days, most of the nerve fibres had changed into fibrous tissue around which bleeding and small vessels containing erythrocytes were prominent. From these findings, it is postulated that the pathological change in the Fallopian canal of six of the temporal bones resulted from acute congestion after birth (due to acute reduction of oxygen density in the arterial blood resulting from severe congenital heart disease), while that of the remaining temporal bone resulted from chronic congestion which had already existed during gestation. It may be concluded that disturbance of blood flow is likely to occur from and distal to the tympanic portion of the Fallopian canal and that this may be due to the peculiar structure of the blood vessels in this area.

Bone Diseases↗
PubMed1987

Subglottic neurofibroma in a child.

Reported here for the first time is a case of subglottic neurofibroma in an infant which was removed by laryngofissure. Neurofibromas are ubiquitous in distribution, but very rare in the larynx and also extremely rare in infancy. Only 9 cases had been reported in children under 9 years of age. In the present case, H.T., a boy aged 2 years and 7 months, complaining of inspiratory stridor since the beginning of December 1985, was admitted to our hospital on Jan. 21, 1986. The tumor was completely removed by laryngofissure and pathological diagnosis showed it to be a neurofibroma. Laryngeal neurofriboma cases are reviewed and discussed.

Child, Preschool↗
PubMed1987

[Neo-adjuvant chemotherapy with UFT and adriamycin in head and neck cancer].

Thirty-one patients with head and neck cancer were administered pretreatment induction chemotherapy (so-called neo-adjuvant chemotherapy) consisting of a UFT and ADM combination. The chemotherapy consisted of ADM (0.5 mg/kg b.w.) once a week up to 3 times, and UFT (600 mg/day) every day for 20 days. Overall response rate was 37.9% (11/31), and 1 CR and 10 PR were obtained. After definitive treatment, the primary control rate was 80.6% (25/31). Sixteen primary lesions in the 31 patients were classified according to Shimosato's grading system into 1 grade IV, 5 grade III and 10 grade II b a-I. Lymph-node metastases in 5 cases were also classified. The grading of lymph-node metastases was lower than that of the primary lesions.

Adult↗
PubMed1986

Intravenous digital subtraction angiography for patients with positional nystagmus.

Thirty cases of intractable positional vertigo were studied by means of digital subtraction angiography (DSA). Benign paroxysmal positional vertigo was not included. DSA allows real time digital subtraction of X-ray transmission data using an image intensifier and television system. Intravenous DSA (IV DSA) was used to compare blood vessel flow in the right and left vertebral arteries. Abnormal findings were noted in 27 patients, with 10 being affected on the left side, 7 on the right, and 10 bilaterally. Twenty-three patients had slight stenosis, and bending and kinking were observed in 17. DSA results were related to the 6 established types of positional nystagmus. DSA is, therefore, considered to be an important tool in the diagnosis and treatment of positional vertigo.

Adult↗
PubMed1985

The use of allograft stapes.

Since 1981, we have used the stapes allograft, singly or in combination with homograft incus, in 20 cases of tympanoplasty and in 7 cases of fixed stapes. All of the allograft stapes discussed were procured, processed and stored in 1980 by the Hyogo Ear Bank, the first to be established in Japan. The stapes allograft was used in three situations: an intact posterior canal wall, an open mastoidectomy cavity, or a fixed stapes (postinflammatory, congenital or otosclerotic). Two modalities of positioning of the donor stapes were attempted: (1) the allograft stapes was placed in the normal position and a shaped incus or cortical bone or tragal cartilage was placed on the top of the stapedial head and connected and (2) the allograft stapes was placed in the upside-down position and the columella was placed on the stapes footplate. Better results were obtained with the allograft stapes placed in the normal position. A two-stage operation, first to place an allograft stapes in the normal position with myringoplasty and then ossiculoplasty, was preferable to one-stage middle ear surgery.

Audiometry, Pure-Tone↗
PubMed1985

Malignant lymphoma in unusual areas of the head and neck: parapharyngeal space and temporal fossa.

Primary malignant lymphomas of the parapharyngeal space are rare and only 28 cases are known to have been reported. No case of malignant lymphoma arising in the temporal fossa has been previously documented. The present paper reports a case of primary non-Hodgkin's lymphoma of the parapharyngeal space in a child and two cases of lymphoma of the temporal fossa in adults. All three cases were diagnosed histopathologically from biopsy specimens as diffuse, B-cell lymphomas. For diagnosis, inspection and bimanual palpation were most important in the parapharyngeal case and the temporal cases required more than one biopsy for the final diagnosis.

Adolescent↗
PubMed1985

Cholesteatoma auris congenita arising from microtia.

The external auditory canal opens medial to lateral in embryonal development. It is obvious that a developmental arrest anywhere during this stage would produce an absence or discontinuity of the canal, that is, congenital atretic ear. Whether or not the obliterative tissue has a bony structure, cholesteatoma can be formed behind it. Microtia is usually associated with an atretic meatus, and it may involve the possibility of epithelial cyst or cholesteatoma. The diagnosis can usually be made by the finding of tender swelling in the deformed auricle or its surroundings. On occasions, it may become necessary to distinguish these conditions from secondary infection of an epidermal cyst on the auricular surface. Several recurrent painful swellings on the deformed auricle in spite of conservative treatment indicate the need for routine otologic radiographs.

Adolescent↗