Biomedical subjects

T M Cink

Publications and source records attributed to T M Cink.

4 recordsLinked to original sources

PubMed1994

Percutaneous large-core breast biopsy: a multi-institutional study.

PURPOSE: To assess the reliability and reproducibility of automated large-core breast biopsy. MATERIALS AND METHODS: A consortium of 20 institutions reported, in a standardized fashion, their core breast biopsy data. All biopsies were performed with "long-throw" (2.3-cm) automated core biopsy devices fitted with 14-gauge needles. Needle guidance was accomplished by means of either a dedicated, stereotaxic device, in which the patient lies in the prone position, or high-frequency electronically focused ultrasound equipment. RESULTS: The data in 6,152 lesions were gathered. Clinical or surgical follow-up was available in 3,765 lesions; 1,363 of these lesions were subsequently surgically excised, and the core histologic study showed cancer in 910 lesions, mammary intraepithelial neoplasia in 173 lesions, and benign disease in 280 lesions. In these 280 lesions, there were 15 false-negative core biopsies. CONCLUSION: The data show that percutaneous large-core breast biopsy is a reproducible and reliable alternative to surgical biopsy.

Biopsy, Needle↗

PubMed1993

Uncomplicated asthma in adults: comparison of CT appearance of the lungs in asthmatic and healthy subjects.

A study was undertaken to define the computed tomographic (CT) appearance of the lungs in subjects with uncomplicated asthma and to compare the prevalence of bronchial dilatation at CT in asthmatic and healthy subjects. Clinical features, pulmonary physiologic findings, chest radiographs, and high-resolution CT scans of 48 asthmatic subjects were reviewed. Forty-one (85%) of the 48 asthmatic subjects were undergoing bronchodilator therapy, 28 (58%) were undergoing steroid therapy, and 21 (44%) were cigarette smokers. Twenty-seven healthy control subjects underwent limited high-resolution CT. At selected CT levels, any bronchus with an internal diameter greater than that of the accompanying pulmonary artery was considered dilated. In the asthmatic subjects, 153 (36%) of 429 bronchi evaluated met criteria for bronchial dilatation compared with 37 (26%) of 142 bronchi in the control group (P < .05). Because bronchial dilatation demonstrated at CT did not correlate with clinical data, the authors conclude a bronchus larger in diameter than the adjacent vessel is not sufficient evidence to diagnose cylindric bronchiectasis.

Adult↗

PubMed1993

Operation Everest. II: Spirometric and radiographic changes in acclimatized humans at simulated high altitudes.

We report spirometry and radiographic data on eight normal male human subjects during prolonged graded altitude exposure to as high as 8,848 m above sea level in a hypobaric chamber. We found a significant and progressive drop in FVC by 14 +/- 3% over 40 days, which resolved slowly during the first 48 h after descent. With altitude, midrange forced expiratory flow (FEF25-75) increased by 82 +/- 3%, probably because of reduced air density. FEV1, however, did not change. Chest radiographs on subjects taken 2 h after descent to sea level showed a pattern of pulmonary artery enlargement and interstitial edema. These data suggest that increased pulmonary blood volume and edema may be causes of the restricted pulmonary function pattern.

Acclimatization↗

PubMed1991

Imaging of the expanded polytetrafluoroethylene prosthetic diaphragm following extrapleural pneumonectomy for mesothelioma.

Extrapleural pneumonectomy, which usually requires placement of a prosthetic hemidiaphragm, can be offered to approximately 24% of patients with malignant mesothelioma. Expanded polytetrafluoroethylene (Gore-Tex) has superior physical characteristics for diaphragmatic grafting and is the material of choice at the authors' institutions. This article describes conventional radiography and computed tomography findings in three patients who underwent extrapleural pneumonectomy. A freshly placed Gore-Tex prosthetic diaphragm appears as a radiolucent crescent-shaped band at the inferior border of the hemithorax and could be confused with a pneumoperitoneum. With time, the lucent crescent becomes thinner and eventually becomes radiopaque; it may be confused with a calcified diaphragm.

Calcinosis↗