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PubMed · 7972743

Percutaneous large-core breast biopsy: a multi-institutional study.

S H Parker·F Burbank·R J Jackman·C J Aucreman·G Cardenosa·T M Cink·J L Coscia·G W Eklund·W P Evans·P R Garver
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Abstract

PURPOSE: To assess the reliability and reproducibility of automated large-core breast biopsy. MATERIALS AND METHODS: A consortium of 20 institutions reported, in a standardized fashion, their core breast biopsy data. All biopsies were performed with "long-throw" (2.3-cm) automated core biopsy devices fitted with 14-gauge needles. Needle guidance was accomplished by means of either a dedicated, stereotaxic device, in which the patient lies in the prone position, or high-frequency electronically focused ultrasound equipment. RESULTS: The data in 6,152 lesions were gathered. Clinical or surgical follow-up was available in 3,765 lesions; 1,363 of these lesions were subsequently surgically excised, and the core histologic study showed cancer in 910 lesions, mammary intraepithelial neoplasia in 173 lesions, and benign disease in 280 lesions. In these 280 lesions, there were 15 false-negative core biopsies. CONCLUSION: The data show that percutaneous large-core breast biopsy is a reproducible and reliable alternative to surgical biopsy.

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Biopsy, NeedleBreastBreast NeoplasmsFemaleHumansRadiography, InterventionalReproducibility of ResultsRetrospective StudiesStereotaxic TechniquesUltrasonography, InterventionalJournal ArticleMulticenter Study

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S H Parker, F Burbank, R J Jackman, C J Aucreman, G Cardenosa, T M Cink, J L Coscia, G W Eklund, W P Evans, P R Garver. 1994. Percutaneous large-core breast biopsy: a multi-institutional study.. https://doi.org/10.1148/radiology.193.2.7972743

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Targeting difficult accessible breast lesions: MRI-guided needle localization using a freehand technique in a 3.0 T closed bore magnet.

PURPOSE: To report the accuracy of magnetic resonance imaging (MRI)-guided needle localization for diagnosis of MRI detected suspicious breast lesions located in difficult accessible regions of the breast, using the freehand method in a 3.0 T closed bore magnet. MATERIALS AND METHODS: In five patients with five MRI-only breast lesions underwent MRI-guided needle localization for histopathologic evaluation of the lesions. All interventional procedures were performed in a 3.0 T MRI system with the patient in prone position and by using a dedicated phased array breast coil. MRI-guided needle localizations were performed by using a freehand technique. In our study, the high-resolution scan allowed preprocedural localization of all lesions without use of contrast enhancement. In all cases contrast-enhanced MRI was performed after insertion of the wire to confirm the tip of the wire in direct contact with the enhancing lesion. RESULTS: Needle localizations were performed in five patients. Histopathologic evaluation of tissue after surgery excision biopsy revealed one lymph node, three invasive ductal carcinoma and one ductal carcinoma in situ. Lesion size varied from 6 to 30 mm. Mean duration time was 25 min. No complications occurred during the intervention method. In the patient with the benign lesion control MRI of the breast after 6 months confirmed lesion removal. CONCLUSIONS: MRI-guided needle localization by using a freehand technique in a 3.0 T closed bore magnet is a safe and accurate method for diagnosis of difficult accessible breast lesions only visible on MRI.

Biopsy, Needle↗