A radioimmunoassay of human circulatory dopamine-beta-hydroxylase.
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Animals↗
Biomedical subjects
T Ouchi
Publications and source records attributed to T Ouchi.
[Estimation of human serum dopamine-beta-hydroxylase activity].
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Child↗
Cerebral dysautoregulation in central neurogenic orthostatic hypotension (Shy-Drager syndrome).
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Angiotensin II↗
[Studies on solubilizing agents. V. Nuclear magnetic resonance studies on the mixtures of glycols and their derivatives with water].
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Glycols↗
A neutral proteinase from Streptomyces naraensis. 3. An improved purification and some physiochemical properties.
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Amino Acids↗
Effect of regional cerebral blood flow of compression by a mass lesion.
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Animals↗
[Studies on solubilizing agents. IV. Dielectric constant correlations with drug solubility in the mixtures of glycols and their derivatives with water].
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Caffeine↗
[Experimental study on local circulation in the brain--especially on the thalamic circulation by polarographic measurement of oxygen tension].
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Acetylcholine↗
Stimulatory effect of adenosine triphosphate and magensium on the release of catecholamines from adrenal medullary granules.
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Adenosine Triphosphate↗
[Mechanism of the antihypertensive effect of alpha-methyldopa (experimental study using blood platelets as the medium)].
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Blood Platelets↗
[Diagnosis and treatment of rheumatoid arthritis].
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Adolescent↗
Abnormal hemispheric blood flow and metabolism in cerebrovascular disease. I. Disordered patterns of hemispheric metabolism.
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Adult↗
Abnormal hemispheric blood flow and mtabolism in cerebrovascular disease. II. Therapeutic trials with 5 per cent CO 2 inhalation, hyperventilation and intravenous infusion of THAM and mannitol.
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Adult↗
Effect of intravenous infusion of glycerol on hemispheric blood flow and metabolism in patients with acute cerebral infarction.
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Aged↗
Impaired neurogenic cerebrovascular control and dysautoregulation after stroke.
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Adult↗
Effects of alpha adrenergic blockade on autoregulation and chemical vasomotor control of CBF in stroke.
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Adult↗
Cerebral metabolic changes during treatment of subacute cerebral infarction by alpha and beta adrenergic blockade with phenoxybenzamine and propranolol.
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Adult↗
Release behaviour of 5-fluorouracil from chitosan-gel microspheres immobilizing 5-fluorouracil derivative coated with polysaccharides and their cell specific recognition.
In order to provide a device releasing drugs in a controlled manner and having targetability to specific organs or cells, chitosan-gel microspheres, CMS, crosslinked with glutaraldehyde, immobilizing 1-[N-(5-aminopentyl) carbamoyl]-5-fluorouracil, 1, coated with anionic polysaccharides, such as 6-O-carboxymethyl-N-acetyl-alpha-1,4-polygalactosamine (CM-NAPGA), 6-O-carboxymethyl-chitin, alginic acid and heparin, by polyelectrolyte complex membrane formation were prepared. When chitosan was crosslinked with glutaraldehyde, 1 was simultaneously immobilized into CMS by Schiff's base formation. Average diameter of CMS obtained was estimated to be about 0.5-1.0 micron by SEM observation. In physiological saline media, only free 5-FU was released from the CMS but 1 and any 5-FU derivative was not. Release rate of 5-FU from the CMS was reduced by coating with polyelectrolyte complex membrane of cationic chitosan and anionic polysaccharides. CMS coated with CM-NAPGA showed a lectin-mediated specific aggregation phenomenon by addition of Abrus precatorius agglutinin. Moreover, the CMS immobilizing 1 coated with CM-NAPGA showed higher growth-inhibitory effect against SK-Hep-1 (human hepatoma) cells in vitro than the CMS coated with other polysaccharides.
Carcinoma, Hepatocellular↗