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Biomedical subjects

T Setogawa

Publications and source records attributed to T Setogawa.

At least 73 records · Page 4Linked to original sources
PubMed1991

Recurrent mixed tumor of the right lacrimal gland causes acute contralateral visual loss.

A 23-year-old woman underwent excisional biopsy of a right palpebral mass: the histopathologic study showed a benign mixed tumor of the lacrimal gland. Thereafter, the tumor recurred repeatedly, and multiple excisions were done. Subsequently, right orbital exenteration was performed, and some orbital and frontal bones were removed. When the patient was 52 years old, the orbital tumor recurred. A histopathologic study revealed malignant transformation. At the age of 54 years, the patient suffered acute loss of vision in her left eye. Computed tomography disclosed invasion of the tumor into the posterior paranasal sinuses and brain.

Adenoma↗
PubMed1991

Presumed iris metastasis from abdominal neuroblastoma.

A 2-month-old infant had a retroperitoneal tumor and increased levels of vanillylmandelic acid and homovanillic acid in the urine, indicating an abdominal neuroblastoma. Two whitish masses that were noted on the left iris regressed in synchrony with the primary tumor mass as therapy was administered. We believe that our patient represents the third reported case of iris metastasis from abdominal neuroblastoma.

Homovanillic Acid↗
PubMed1991

Ophthalmic complications in patients with paranasal sinus mucopyoceles.

We examined 45 (23 male and 22 female) Japanese patients with paranasal sinus mucopyoceles associated with ophthalmic complications. The patients ranged in age from 31 to 87 years. The patient distribution by the affected sinus was as follows: maxillary sinus alone, 17 patients; ethmoidal sinus alone, 9 patients; frontoethmoidal sinuses, 9 patients; frontal sinus alone, 7 patients, and other multiple sinuses, 3 patients. Thirty-nine mucoceles and 6 pyoceles were identified. Ophthalmic signs and symptoms included lid swelling, ocular pain, pseudoptosis, proptosis, displacement of the eyeball, epiphora, slight blurring of vision, severely decreased visual acuity, visual field abnormality, diplopia, disk edema, retinoichoroidal folds and increased intraocular pressure. Of the 45 patients, 1 had a history of sinus trauma and 29 had a history of sinus surgery.

Adult↗
PubMed1991

Orbital tumor in an infant with acute monocytic leukemia associated with chromosome 5q-,t(9p-11q+),11p+.

We examined an 8-month-old infant with left proptosis, chemosis and orbital mass. A computed tomographic scan revealed a left orbital tumor. An anorectal nodule was also found. Results of the hematologic study showed poorly differentiated acute monocytic leukemia (M5 according to the French-American-British classification). Chromosomal analysis disclosed 46, XX,5q-,t(9p-;11q+),11p+. We believe that our patient represents a rare case of orbital tumor in acute monocytic leukemia associated with chromosomal abnormalities.

Chromosome Aberrations↗
PubMed1991

Optic nerve hypoplasia associated with porencephalia in a girl and retinitis pigmentosa in her sister.

An 18-year-old women (case II-4) had decreased visual acuity, visual-field defects and small optic disks bilaterally that remained unchanged for a follow-up period of 9 years. The patient also had an abnormal cavity within the cerebral hemispheres. Her 29-year-old sister (case II-1) had night blindness, bone corpuscle pigmentation in mottled retinas and nonrecordable electroretinographic responses bilaterally. We believe that the occurrence of optic nerve hypoplasia associated with porencephalia in one patient and retinitis pigmentosa in her eldest sister may be rare.

Adolescent↗
PubMed1991

Pigmented paravenous retinochoroidal atrophy in a 68-year-old man.

A 68-year-old man with patchy paravenous zones of retinal degeneration with bone spicule pigmentation OU was diagnosed as having pigmented paravenous retinochoroidal atrophy. We reviewed the literature and found 71 previously reported cases of this condition. Most of the affected individuals were young adults. By comparison, our patient was afflicted at a considerably older age.

Aged↗
PubMed1991

Disc edema in juvenile retinitis pigmentosa.

A 1-year-old girl had esotropia and bilateral mottled retina. At age 2 years, she had night blindness. At age 12 years, she had poor visual acuity, nystagmus, mottled retina, and unrecordable electroretinograms OU and a whitish swollen optic disc with retinal folds OD. We believe that this patient had an uncommon association of disc edema with juvenile retinitis pigmentosa.

Esotropia↗
PubMed1990

Subretinal hemorrhages with or without choroidal neovascularization in the maculas of patients with pathologic myopia.

We examined 20 patients (24 eyes) who had refractive errors of -8 diopters or more and subretinal hemorrhages at the initial visit. They were divided into two groups according to fluorescein angiographic findings: 15 eyes without choroidal neovascularization (CNV) and 9 eyes with CNV. Subretinal hemorrhage without CNV was frequent in patients aged 20-39 years (mean, 36.8 years). CNV was common in patients aged 60-79 years (mean, 61.0 years). No relationship was noted between refractive error and type of hemorrhage. In the eyes without CNV, the subretinal hemorrhages disappeared spontaneously after a few months. The visual acuity of these patients was variable at the initial visit (range, 0.01-0.8), and was unchanged or improved during the follow-up period. In the eyes with CNV, the visual acuity was less than 0.1 at the initial visit and was unchanged or worse during the follow-up period.

Adult↗
PubMed1990

Cutaneous eruption with or without ocular complications in patients with herpes zoster involving the trigeminal nerve.

We examined 62 patients with acute herpes zoster involving the trigeminal nerve; 13 had eruptions only and 49 (51 eyes) had eruptions with ocular complications. Bilateral involvement was found in two patients. The frequency of the disease appeared to increase with age, and the disease was least active in November. Patients with eruptions only demonstrated affected areas along the first, second, and/or third divisions of the trigeminal nerve. Ocular complications occurred in patients who had eruptions along the first and/or second divisions of the nerve, and they were usually noted in patients with eruptions on the tip and one side of the node. The ocular complications and associated systemic conditions varied.

Adolescent↗
PubMed1990

Test results in patients with Sjögren's syndrome defined by the Japanese criteria.

We examined 123 patients (mean age, 63.4 years) with Sjögren's syndrome at Shimane Medical University Hospital from 1980 to 1988. According to the Japanese criteria for Sjögren's syndrome, there were 106 definite and 17 probable cases. Female patients were predominant (74.8% to 25.5%). Most patients reported dry eye symptoms and had positive results on the Schirmer's, rose-bengal, and fluorescein tests. Although most patients described dry mouth symptoms, not all showed positive sialogram results, lymphocytic infiltrate on minor salivary glands, decreased salivary secretion, and salivary gland swelling. Connective tissue diseases were present in 28 patients. Most patients had positive antinuclear antibody reactions. Most of our patients who were diagnosed as having Sjögren's syndrome by the Japanese criteria could not be classified as such by the California, Copenhagen, or Greek criteria.

Adult↗
PubMed1990

Corneal endothelial changes after posterior chamber intraocular lens implantation in patients with or without diabetes mellitus.

We examined 96 patients (111 eyes) who underwent extracapsular cataract extraction with the implantation of a posterior chamber intraocular lens. Of 96 patients 24 (29 eyes) with non-insulin-dependent diabetes mellitus had no or simple retinopathy; 72 patients (82 eyes) served as non-diabetic controls. The central corneas of all subjects were photographed by a specular microscope preoperatively and three, six, and 12 months postoperatively. No significant differences in the endothelial cell density, coefficient of variation, or cell loss were noted between diabetic patients and age matched non-diabetic subjects during the observation period.

Age Factors↗
PubMed1990

Causes of subconjunctival hemorrhage.

We examined prospectively 8,726 patients in outpatient eye clinics. A total of 225 (2.9%) patients had subconjunctival hemorrhage. No sexual or age predilection was found. The most common causes for the condition were minor local trauma, systemic hypertension, and acute conjunctivitis. Subconjunctival hemorrhages resulting from local trauma were frequent in the summer, and those associated with systemic hypertension were noted most often in older patients. Blood pressures should be examined in patients with subconjunctival hemorrhages, particularly in older patients.

Adolescent↗
PubMed1990

Pericentral retinal degeneration deteriorates during pregnancies.

A 25-year-old pregnant woman complained of a transient decrease of vision in her left eye. No ring scotoma was described. During her second pregnancy at age 27, the patient noticed subtle ring scotomas in both eyes. During her third pregnancy at age 30, the scotomas enlarged. A grayish zone with a few small areas of pigmentation around the macula was seen bilaterally. At age 37, the retinal degeneration progressed slightly: results of visual function and electrophysiologic examinations revealed mild rod and cone dysfunction. We believe that this patient represents a rare case of deteriorating pericentral retinal degeneration during pregnancies.

Adult↗
PubMed1990

Myelinated retinal nerve fibers: prevalence, location and effect on visual acuity.

We examined fundus photographs of 5,789 patients (11,578 eyes) and found 39 patches of myelinated nerve fibers in 35 eyes of 33 patients. The prevalence was 0.57%. The lesion was more frequent in females than in males. The patch occurred more often at the superior sectors of the nerve head and in the inferotemporal retina than in other areas. No myelinated nerve fibers were discovered in the macula. One patient (case 1) had 3 patches in 1 eye. Two patients (cases 2 and 3) had unilateral myelinated nerve fibers, bilateral myopia and ipsilateral amblyopia. In case 3, the patch was associated with an epiretinal membrane. Another patient (case 4) had branch vein occlusion and neovascularization from the patch of myelinated nerve fibers. The fundus conditions observed in our cases 1-4 may be uncommon.

Adolescent↗
PubMed1990

Abnormally distributed branches of the retinal vessels, enlarged macular arteries and long cilioretinal arteries.

We examined fundus photographs of 3,506 eyes and noted uncommon retinal vessel patterns in the temporal quadrants of the posterior fundus. Of 1,753 subjects, 20 patients (21 eyes) had unusual retinal vessel patterns. Seven eyes had an abnormally distributed branch of the inferotemporal artery; 8 eyes had an enlarged macular artery. Of these 20 patients, 1 had visual complaints associated with the unusual vascular patterns.

Adult↗
PubMed1990

Sex differences in the susceptibility of mice to infection induced by Mycobacterium intracellulare.

Sex differences in the susceptibility of Balb-c mice to Mycobacterium intracellulare infection were studied. When mice were given M. intracellulare intravenously, macroscopic lesions were considerably more extensive in the lungs, liver, and kidneys of male mice than in female mice. A significantly more marked growth of organisms occurred in these visceral organs of the male mice during the course of infection for as long as 16 wk after the challenge. This difference can be partly explained by the finding that the antimicrobial activity of host peritoneal macrophages is more potent in the female mice.

Animals↗
PubMed1990

Anomalous macular vessels: case report and review of the recent Japanese literature.

We examined a 19-year-old woman with large macular vessels who had temporarily impaired visual acuity. The anomalous macular vessels had arteriovenous shunts and were associated with abnormal capillary networks. In a review of the recent Japanese literature, we found another eight patients with anomalous macular vessels who had undergone fluorescein angiography. We prefer the term anomalous macular vessels to describe this condition.

Adult↗