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T V Balueva

Publications and source records attributed to T V Balueva.

58 records · Page 4Linked to original sources
PubMedDate not supplied

[Mechanisms of responses of systemic circulation: role of endothelial factor in the vascular tone regulation].

Experimental data on the effect of NO synthase inhibition on hemodynamic changes (blood pressure, cardiac output, and peripheral resistance) induced by an increased (polyglucin infusion) or decreased (orthostasis) cardiac output are presented. Under conditions of NO synthase inhibition, the pressor effects of polyglucin and orthostatic hypotension increased by 70 and 72%, respectively. The response of peripheral resistance had a similar trend. Significance of NO secretion by vascular endothelium for the development of systemic hemodynamic responses is proposed.

Animals↗
PubMedDate not supplied

[The no-dependent mechanism of the orthostatic reaction of system hemodynamics in rats].

The aim was to describe endothelium-dependent reactions of system hemodynamics to the reduction in system blood circulation (cardiac output) by orthostatic positioning of anesthetized rats. Head rise at 15, 30 and 45 degrees and NO synthesis depression increased the hypotensive reaction to orthostasis by 32, 60 and 71%, respectively, as compared with values prior to the block. This allows the conclusion concerning the recruitment of an NO-dependent vasodilative mechanism in vascular control. It was shown that NO modulated the arterial system reactivity to orthostasis the magnitude of which depended on baseline blood pressure. This relationship was reverse in the event of intact NO-synthase and linear in the event of NO synthesis depression. These data point to the significance of NO secretion for as baseline BD values, so mechanisms of orthostasis-induced hypotension.

Animals↗
PubMedDate not supplied

[The effect of the initial (controllable) tonus of arterial vessels on the formation of systemic pressor reactions].

A significant decrease of systolic and diastolic effects occurred when initial level of the blood pressure had been elevated from 60 to 200 mm Hg with mesathone and from 70 to 185 mm Hg with polyglukine in anaesthesized rats. A reverse linear correlation was found between the above parameters at a high degree of connection for both agents. "Vascular" and "cardiac" mechanisms of revealed relationships are discussed.

Angiotensin II↗