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T V Koronelli

Publications and source records attributed to T V Koronelli.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

[Biological activity of a polar lipid of Clostridium butyricum spores].

A fraction of polar lipids was isolated from spores of the anaerobic bacterium Clostridium butyricum 35/11 exerting a noticeable radioprotective effect. The main biological activity of spore extracts was associated with this fraction. The fraction of polar lipids inhibited autolysis of the bacterial cell walls. The fraction was found to contain a phenolic glycolipid and a peptide component. The bacteriostatic and radiotherapeutic properties of the fraction are presumed to be due to its membranotropic activity.

Animals↗
PubMedDate not supplied

[Action of isoniazid on the growth of saprophytic mycobacteria].

The effect of isoniazide on the ability to assimilate hydrophilic (sugars) and hydrophobic (hydrocarbon) substrates was studied with saprophytic mycobacteria. The minimal concentration of isoniazide inhibiting the growth of saprophytic mycobacteria in a medium containing hexadecane was 150 mcg/ml. If isoniazide was added at a concentration of 900 mcg/ml at the beginning of the logarithmic growth phase, the growth was sharply inhibited and assimilation of the hydrocarbon decelerated 4 times. The same concentration of isoniazide hardly affected the growth of the saprophytic mycobacteria in a medium containing a carbohydrate.

Carbohydrate Metabolism↗
PubMedDate not supplied

[Hydrocarbon-oxidizing microflora of uncontaminated seawater].

The distribution of hydrocarbon-oxidizing microflora in noncontaminated sea waters was studied in the northern region of the Pacific Ocean in the vicinity of the Copper Island. The total number of microorganisms was assayed as well as the number of heterotrophic, oligocarbophilic and hydrocarbon-oxidizing microorganisms. Oligocarbophilic bacteria were the most abundant group (from 120 to 24,000 cells per 1 ml), and predominated in 12 stations among 23. The number of heterotrophic organisms was not great and did not exceed 200 cells per 1 ml in 13 stations. A solid medium with an oil product (1%) which was used to determine the number of hydrocarbon-oxidizing bacteria gave overstated results due to the growth of oligocarbophilic forms that could survive in the presence of high hydrocarbon concentrations in the medium. A silica gel medium with an oil product is recommended. Despite the absence of oil contaminations in littoral waters, hydrocarbon-oxidizing bacteria were found in all samples and their content was high in some stations. This can be accounted for by the variety of nutrient requirements of these microorganisms and, apparently, by the presence in water of high molecular weight aliphatic lipids inding the capacity to oxidize hydrocarbons. Organisms belonging to the genera Mycobacterium and Arthrobacter prevailed among hydrocarbon-oxidizing bacteria.

Hydrocarbons↗
PubMedDate not supplied

[Lipids of saprophytic bacteria produced during growth on a complex organic substrate].

The composition of lipids and the structure of mycolic acids were studied in Mycobacterium lacticolum var. aliphaticum isolated from soil and grown on MPB. The lipids of all strains were found to contain phosphatidyl inositol mannosides, phosphatidyl ethanolamine, cardiolipin, mycolic and common fatty acids, triglycerides, wax, and several unidentified compounds. The structure of mycolic acids was established by mass spectrometry. The mycolic acids C34:0, C35:0 and C36:0 prevailed in strain 175, and the mycolic acids C34:1, C34:0, C36:1 and C36:0 predominated in strain 180. The composition of minor components was assayed. Variations in the composition of mycolic acids depending on the source of carbon in the medium are discussed.

Chemical Phenomena↗