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T Vik

Publications and source records attributed to T Vik.

61 records · Page 4Linked to original sources

The vitamin D status of man at 70 degrees north.

The overall vitamin D status of man at 70 degrees north has been evaluated by measuring the total 25-hydroxy-vitamin D (25-OHD) in serum samples from seventeen healthy adults from September 1977 to September 1978. The lowest 25-OHD-concentration was found in March (mean 51.5 nmol/l, SD = 19.5). This was significantly lower than in July and September 1977 and 1978 (P less than or equal to 0.0006). Of particular interest was the highly significant rise in the 25-OHD-concentration from March to July, most probably reflecting sun-induced endogenous synthesis in the skin. Despite the sun being below the horizon for two of the winter months, the 25-OHD-concentration remained at a constant and fairly high level (50-55 nmol/l).

Adult↗

The activity of gamma-glutamyltransferase after bile duct ligation in guinea pig.

The activity of gamma-glutamyltransferase was studied in guinea pig after bile duct ligation. In serum, an abrupt increase in activity up to 10--20 times the normal value was found 3 h after obstruction and the mean activity over the first 3 days following the operation was some 8 times the normal value. In liver, however, a small decline in activity could be demonstrated. The administration of cycloheximide did not influence the acute increase in serum activity. Bile duct ligation caused marked increases in serum bile acid levels which initially paralleled the serum gamma-glutamyltransferase activity. It is suggested that the increased serum activity may arise from the solubilization by bile acids of liver membrane-bound enzyme.

Alkaline Phosphatase↗