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Biomedical subjects

T Wegmann

Publications and source records attributed to T Wegmann.

At least 37 records · Page 2Linked to original sources

[Particular features of mycotic carriers (author's transl)].

Although we are all carriers of fungi, an infection is rare. Therefore, the following questions are discussed: Why do these actually saprophytic germs become pathogenic at all? Why have opportunistic fungus infections increased? The diagnosis of a fungus infection due to saprophytic pathogens is difficult, as the demonstration of a fungus does not necessarily imply disease. The case history with relevant predisposing factors is an essential clue to the diagnosis. As a matter of principle, the diagnosis of a systemic mycosis should only be established by exclusion.

Drug-Related Side Effects and Adverse Reactions↗

[Fungi in pulmonary pathology].

The author presents the most frequently observed pulmonary infections due to some opportunistic fungi (yeast, Aspergillus, Mucor). He describes the criterial for a correct diagnosis of pulmonary mycosis.

Adolescent↗

[Atypical mycobacterial infection due to Mycobacterium fortuitum].

The case is presented of a 48-year-old woman who, in association with repeated septic temperatures, developed abscesses in the region of the right shoulder and in the right ankly. Histological examination from excisates revealed caseous tuberculoid granulomas. Mycobacterium fortuitum was isolated from the pus of both abscesses. Although the Mycobacterium fortuitum was resistant to nine commonly used tuberculostatics, it was found to be sensitive to ethionamide and capreomycine. The use of these two drugs in combination with local measures proved successful.

Ankle↗

[Indications for rabies vaccination and prophylactic immunization in man (author's transl)].

Since therapy of an overt attack of rabies fails, we are completely dependent on prophylaxis. This must be carried out with extreme care. A careful detailed history is the most important, the fundamental question being: was this a provoked or unprovoked attack by the animal? In addition some knowledge of the behavior of different animals towards man is essential. Before every treatment, the question whether it is really necessary must be settled. The help of a veterinary colleague should be called upon in taking the history. A rapid diagnosis can be obtained by fluorescence serology of the dead animal.

Bites and Stings↗

[Clinical aspects of lung mycoses].

The clinical picture of pulmonary mycoses is described and discussed. The diagnosis of tropical pulmonary mycoses is--in contrast to the native mycoses--relatively simple with respective serological tests and intracutaneous reactions. For the diagnosis the differentiation of fungi or molds is of utmost importance.

Aspergillosis↗

[Diphtheria epidemic in eastern Switzerland in 1974].

A diphtheria epidemic in the eastern part of Switzerland in 1974 and the measures which were taken for its management and eradication are described. In particular it is pointed out that at present diphtheria displays atypical clinical symptoms in Europe, a fact that renders the diagnosis very difficult in many cases. Therefore, it is important to perform a throat swab in every patient with suspected diphtheria; it is also necessary to explicitly require a search for C. diphtheriae. The early recognition and early treatment of diphtheria with penicillin or erythromycin is of the utmost importance in order to avoid neurological and cardiac complications. With regard to the management and eradication of a diphtheria epidemic, the most important measures are rapid antibiotic protection of all contacts and a widespread immunization of the population. Vaccination of adults with a DiTe vaccine containing a reduced amount of Di-toxoid is recommanded.

Adolescent↗

[Prognosis of purulent meningitis with particular reference to the beginning of treatment and age of the patient (author's transl)].

The relatively high lethality of meningitis is due to the delay in beginning treatment (usually caused by nonrecognition of the disease) and to the greater age of the patient (associated diseases). New aspects of the improvement of the prognosis were not obtained by comparison of various patient collectives a decade apart in our clinic, although an improvement in additional measures such as artificial respiration occurred. The reason lies in veiling by antibiotic premedication. Before beginning antibiotic therapy an exact etiological diagnosis should be made. This objective can only be attained by better training of the physician, including neurology.

Adolescent↗

[Laxative induced diarrhea- -a form of self-mutilation].

In the differential diagnosis of gastrointestinal disturbances the possibility of laxative abuse is considered either too late or not at all. The sequel is a protracted course of illness with a series of expensive and fruitless investigations. On the basis of three recently observed cases of laxative-induced diarrhea the problems of diagnosis and management are discussed. Methods of securing early diagnosis are mentioned. The overall prognosis must be considered unfavorable. The importance is stressed of long-term follow-up of these patients at community level, to ensure timely intervention should complications arise and to prevent further unnecessary investigations.

Adult↗